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The LexA Repressor Binds Within the Deep Helical Groove of the Activated RecA Filament
Journal of Molecular Biology, 1993The RecA protein of Escherichia coli, as a result of DNA damage, catalyzes the cleavage of its own repressor, the LexA protein, and thereby initiates the SOS response. Using a non-cleavable LexA mutant, we have obtained a co-complex of both the RecA and LexA proteins on DNA.
X, Yu, E H, Egelman
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LexA, the Self-Cleaving Transcriptional Repressor of the SOS System
1993All living organisms are permanently exposed to variable amounts of chemical or physical agents which can form adducts with the cellular constituents. A particularly sensitive target is DNA due to its low copy number and its central role in the storage and readout of information for setting up the cell.
M. Schnarr, M. Granger-Schnarr
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Biochemistry, 1985
A rapid large-scale procedure for the purification of the LexA repressor of Escherichia coli is described. This procedure allows one to get more than 100 mg of purified protein from 100 g of bacterial paste with a purity of at least 97%. This method is comparable to earlier, far more complicated purification procedures giving clearly smaller yields. It
M, Schnarr +3 more
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A rapid large-scale procedure for the purification of the LexA repressor of Escherichia coli is described. This procedure allows one to get more than 100 mg of purified protein from 100 g of bacterial paste with a purity of at least 97%. This method is comparable to earlier, far more complicated purification procedures giving clearly smaller yields. It
M, Schnarr +3 more
openaire +2 more sources
Molecular Microbiology, 1994
SummaryThe LexA repressor controls the expression of several genes, including lexA, recA, and sfiA, which are induced when exponentially growing bacteria are exposed to DNA‐damaging agents, Induction of this so‐called SOS response takes place while LexA is cleaved in a reaction that requires the RecA protein and damaged DNA.
A M, Dri, P L, Moreau
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SummaryThe LexA repressor controls the expression of several genes, including lexA, recA, and sfiA, which are induced when exponentially growing bacteria are exposed to DNA‐damaging agents, Induction of this so‐called SOS response takes place while LexA is cleaved in a reaction that requires the RecA protein and damaged DNA.
A M, Dri, P L, Moreau
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JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
Nature, 2007Bryan C Thines +2 more
exaly
DWARF 53 acts as a repressor of strigolactone signalling in rice
Nature, 2013Xue Liu, Lei Wang, Xiangbing Meng
exaly