CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs. [PDF]
, 2018 Regeneration following tissue damage often necessitates a mechanism for cellular re-programming, so that surviving cells can give rise to all cell types originally found in the damaged tissue. This process, if unchecked, can also generate cell types that
Alexander, Larissa +2 more
core +2 more sources
Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage
Microbial Biotechnology, 2021 Summary SOS box of the recA promoter, PVRecA from Vibrio natriegens was characterized, cloned and expressed in a probiotic strain E. coli Nissle 1917. This promoter was then rationally engineered according to predicted interactions between LexA repressor
Jack X. Chen +5 more
doaj +1 more source
Regulation of the SOS response in Bacillus subtilis: evidence for a LexA repressor homolog [PDF]
Journal of Bacteriology, 1991 The inducible SOS response for DNA repair and mutagenesis in the bacterium Bacillus subtilis resembles the extensively characterized SOS system of Escherichia coli. In this report, we demonstrate that the cellular repressor of the E. coli SOS system, the LexA protein, is specifically cleaved in B.
Martin F. Wojciechowski +2 more
openalex +4 more sources
Expression of Canonical SOS Genes Is Not under LexA Repression in Bdellovibrio bacteriovorus [PDF]
, 2005 The here-reported identification of the LexA-binding sequence of Bdellovibrio bacteriovorus, a bacterial predator belonging to the δ-Proteobacteria, has made possible a detailed study of its LexA regulatory network. Surprisingly, only the lexA gene and a
Campoy, Susana +4 more
core +1 more source
Current Genetics, 2021 Under non-inducing conditions (absence of galactose), yeast structural genes of the GAL regulon are repressed by Gal80, preventing interaction of Gal4 bound to UAS GAL promoter motifs with general factors of the transcriptional machinery.
J. Lettow, R. Aref, H. Schüller
semanticscholar +1 more source
Bacteriophage 434 Hex Protein Prevents RecA-Mediated Repressor Autocleavage
Viruses, 2013 In a λimm434 lysogen, two proteins are expressed from the integrated prophage. Both are encoded by the same mRNA whose transcription initiates at the PRM promoter. One protein is the 434 repressor, needed for the establishment and maintenance of
Paul Shkilnyj +2 more
doaj +1 more source
Early initiation of a replication origin tethered at the nuclear periphery [PDF]
, 2010 Peer reviewedPublisher ...
Ansari +32 more
core +2 more sources
TFIIIC Localizes Budding Yeast ETC Sites to the Nuclear Periphery [PDF]
, 2012 Peer reviewedPublisher ...
Botsios, Sotirios +3 more
core +2 more sources
Transcriptional analysis of the
Microbial Cell Factories, 2006 Background RecA is a highly conserved prokaryotic protein that not only plays several important roles connected to DNA metabolism but also affects the cell response to various stress conditions.
Cordone Angelina +4 more
doaj +1 more source
Biochemical characterization of Borrelia burgdorferi's RecA protein. [PDF]
PLoS ONE, 2017 RecA plays key roles in DNA recombination, replication and repair. Mutation of recA in the Lyme disease spirochete, Borrelia burgdorferi, fails to produce some of the phenotypes expected from study of recA mutation in other organisms.
Shu Hui Huang +5 more
doaj +1 more source