Results 61 to 70 of about 9,038 (230)

Selective alleviation of Mitomycin C sensitivity in lexA3 strains of Escherichia coli demands allele specificity of rif-nal mutations: a pivotal role for rpoB87-gyrA87 mutations. [PDF]

PLoS ONE, 2014
Very recently, we have reported about an unconventional mode of elicitation of Mitomycin C (MMC) specific resistance in lexA3 (SOS repair deficient) mutants due to a combination of Rif-Nal mutations (rpoB87-gyrA87).
Vinod Shanmughapriya, Shanmugaraja Meenakshi, M Hussain Munavar   +2 more
doaj   +1 more source

Reaction of LexA repressor with diisopropyl fluorophosphate. A test of the serine protease model.

Journal of Biological Chemistry, 1990
The LexA repressor of Escherichia coli modulates the expression of the SOS regulon. In the presence of DNA damaging agents in vivo, the 202-amino acid LexA repressor is inactivated by specific RecA-mediated cleavage of the Ala-84/Gly-85 peptide bond. In vitro. LexA cleavage requires activated RecA at neutral pH, and proceeds spontaneously at high pH in
Kenneth L. Roland, John W. Little
openalex   +3 more sources

Design and comparative characterization of RecA variants

Scientific Reports, 2021
RecA plays a central role in DNA repair and is a main actor involved in recombination and activation of the SOS response. It is also used in the context of biotechnological applications in recombinase polymerase isothermal amplification (RPA).
Elsa del Val, William Nasser, Hafid Abaibou, Sylvie Reverchon   +3 more
doaj   +1 more source

The SOS response of Listeria monocytogenes is involved in stress resistance and mutagenesis [PDF]

The SOS response is a conserved pathway that is activated under certain stress conditions and is regulated by the repressor LexA and the activator RecA.
Abee, T., Molenaar, D., Schalkwijk, S., van, Veen, S., van der, Vos, W.M., de, Wells-Bennik, M.H.J.   +5 more
core   +1 more source

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors [PDF]

, 2013
Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we describe a novel signature motif (F/YSXXLXXL/Y) in the developmental regulator BCL11A that facilitates its ...
Aerbajinai, Albers, Aslam, Avram, Avram, Baker, Benoit, Berry, Chun Ming Chan, Cismasiu, Cismasiu, Collins, Coulthard, Cristina Montiel-Duarte, David M. Heery, Escher, Filipe, Frances R. Wadelin, Gui, Gurnell, Hall, Heery, Heery, Hilary M. Collins, Hu, Huang, Huggins, Joel Fulton, Kalkhoven, Kiefer, Kobayashi, Kobayashi, Kruse, Kuo, le Maire, Leid, Lettre, Liberati, Lim, Lin, Lin, Liu, Marban, Menzel, Monaghan, Nagy, Nakamura, Neetu Bharti, Nigel P. Mongan, Paula M. Moran, Peng, Perissi, Rohr, Rouleau, Sankaran, Sankaran, Sankaran, Satterwhite, Senawong, Sheppard, Song, Takezawa, Topark-Ngarm, Torchia, Tsai, Uda, Wang, Watson, Xie, Xie, Xu, Xu, Xu, Yu, Zhang, Zhu   +75 more
core   +2 more sources

RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst [PDF]

, 2006
Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus.
Bellaire, Bryan H., Booth, Natha J., Elzer, Philip H., Ennis, Don G., Gee, Jason M., Kovach, Michael E., Roop, R. Martin II, Roux, Christelle M., Tsolis, Renee M.   +8 more
core   +2 more sources

Nucleotide sequence binding specificity of the LexA repressor of Escherichia coli K-12 [PDF]

Journal of Bacteriology, 1985
The specificity of LexA protein binding was investigated by quantifying the repressibility of several mutant recA and lexA operator-promoter regions fused to the Escherichia coli galactokinase (galK) gene. The results of this analysis indicate that two sets of four nucleotides, one set at each end of the operator (terminal-nucleotide contacts), are ...
K F, Wertman, D W, Mount
openaire   +2 more sources

The Transcription Factors NFYA1 and GBF3 Jointly Regulate CHS2 to Promote Tangeretin Accumulation and Cold Tolerance in Citrus

Plant Biotechnology Journal, EarlyView.
ABSTRACT Tangeretin has been known as a polymethoxylated flavone conferring both phytoprotection and nutraceutical value, but cryoprotective roles and molecular regulation of tangeretin under abiotic stresses remain largely unexplored. In this study, we demonstrated that cold treatment led to greater accumulation of tangeretin and upregulation of ...
Peng Xiao, Jing Qu, Yike Zeng, Wei Xiao, Tian Fang, Yilei Wang, Xi Zeng, Chunlong Li, Ji‐Hong Liu   +8 more
wiley   +1 more source

The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time [PDF]

, 2006
Peer ...
Andrulis ED, Anne D Donaldson, Askree SH, Bermudez VP, Boulton SJ, Bowman GD, Bylund GO, Bystricky K, Cosgrove AJ, Dimitrova DS, Donaldson AD, E Douglas Robertson, Ferguson BM, Gartenberg MR, Gilbert DM, Gilbert N, Gotta M, Gottschling DE, Gravel S, Hanna JS, Hayashi A, Hediger F, Heun P, Heun P, Kenna MA, Kim J, Laroche T, Martin SG, Mayer ML, Merkle CJ, Naiki T, Ohta S, Palladino F, Petronczki M, Porter SE, Raghuraman MK, Raghuraman MK, Roy R, Shin-ichiro Hiraga, Skibbens RV, Smolikov S, Stellwagen AE, Stevenson JB, Strahl-Bolsinger S, Straight AF, Suter B, Taddei A, Taddei A, Tanabe H, Tanaka T, Tham WH, Woodfine K   +51 more
core   +2 more sources

The ZmFKF1b‐ZmDi19‐5 Regulatory Module Coordinates Drought Tolerance and Flowering Time in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought is a major environmental stress that inhibits plant growth and reduces crop yields. The Di19 gene family is known to play a pivotal role in mediating plant responses to drought. However, the mechanisms by which Di19 proteins integrate drought response with developmental processes, particularly flowering time, remain largely unknown in ...
Haixia Zeng, Dandan Dou, Yang Yang, Yan Yan, Yawen Sun, Shuhan Yang, Wen Yao, Shifang Zhao, Mingle Wang, Zhixue Liu, Zhenzhen Ren, Huihui Su, Liru Cao, Lixia Ku, Xu Zheng, Chengwei Li, Yanhui Chen   +16 more
wiley   +1 more source