Results 71 to 80 of about 115,119 (230)

Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10 [PDF]

open access: yes, 2013
The plant hormone jasmonate (JA) activates gene expression by promoting ubiquitin-dependent degradation of JAZ transcriptional repressor proteins. A key feature of all JAZ proteins is the highly conserved Jas motif, which mediates both JAZ degradation ...
Campos, Marcelo L.   +7 more
core   +1 more source

Nucleotide sequence and mutational analysis of an immunity repressor gene from Bacillus subtilis temperate phage ϕ105 [PDF]

open access: yes, 1985
We have identified and sequenced a bacteriophage phi 105 gene encoding an immunity repressor, the first to be characterized from a temperate phage infecting a Gram-positive host.
De Smet, Bea   +3 more
core   +2 more sources

Selective alleviation of Mitomycin C sensitivity in lexA3 strains of Escherichia coli demands allele specificity of rif-nal mutations: a pivotal role for rpoB87-gyrA87 mutations. [PDF]

open access: yesPLoS ONE, 2014
Very recently, we have reported about an unconventional mode of elicitation of Mitomycin C (MMC) specific resistance in lexA3 (SOS repair deficient) mutants due to a combination of Rif-Nal mutations (rpoB87-gyrA87).
Vinod Shanmughapriya   +2 more
doaj   +1 more source

Analysis of the SOS response of Vibrio and other bacteria with multiple chromosomes [PDF]

open access: yes, 2012
Background: The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic ...
Barbé García, Jordi   +3 more
core   +4 more sources

Design and comparative characterization of RecA variants

open access: yesScientific Reports, 2021
RecA plays a central role in DNA repair and is a main actor involved in recombination and activation of the SOS response. It is also used in the context of biotechnological applications in recombinase polymerase isothermal amplification (RPA).
Elsa del Val   +3 more
doaj   +1 more source

The Kinetic and Molecular Basis for the Interaction of LexA and Activated RecA Revealed by a Fluorescent Amino Acid Probe.

open access: yesACS Chemical Biology, 2020
The bacterial DNA damage response (the SOS response) is a key pathway involved in antibiotic evasion and a promising target for combating acquired antibiotic resistance. Activation of the SOS response is controlled by two proteins: the repressor LexA and
Z. M. Hostetler   +4 more
semanticscholar   +1 more source

Bayesian joint modeling of multiple gene networks and diverse genomic data to identify target genes of a transcription factor

open access: yes, 2012
We consider integrative modeling of multiple gene networks and diverse genomic data, including protein-DNA binding, gene expression and DNA sequence data, to accurately identify the regulatory target genes of a transcription factor (TF).
Pan, Wei, Wei, Peng
core   +1 more source

HilE regulates HilD by blocking DNA binding in Salmonella enterica serovar Typhimurium [PDF]

open access: yes, 2018
The Salmonella type three secretion system (T3SS), encoded in the Salmonella pathogenicity island 1 (SPI1) locus, mediates the invasion of the host intestinal epithelium.
Cott Chubiz, Jessica E   +3 more
core   +2 more sources

A role for a small stable RNA in modulating the activity of DNA-binding proteins [PDF]

open access: yes, 1995
The 10Sa RNA, encoded by the E. coli ssrA gene, appears to modulate action of some DNA-binding proteins. When ssrA is inactivated, lacZ expression from the lac operon, as well as galK from a gal operon fused to a phage λ promoter, is reduced from that ...
Friedman, David I., Retallack, Diane M.
core   +1 more source

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