Results 171 to 180 of about 188,329 (316)

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

A protein with similarity to the human retinoblastoma binding protein 2 acts specifically as a repressor for genes regulated by the b mating type locus in Ustilago maydis [PDF]

, 2000
Claudia Quadbeck‐Seeger, Gerhard Wanner, Sieglinde Huber, Regine Kahmann, Jörg Kämper   +4 more
openalex   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

<i>Candida albicans</i> Extracellular Vesicles Upregulate Nrg1 Transcription Repressor to Inhibit Self-Hyphal Development and Candidemia. [PDF]

Int J Mol Sci
Wei Y, Zhou Y, Li B, Wang Z, Liao B, Wang J, Zhou J, Zong Y, Chen D, Shen J, Shi Y, Zhou X, Liao G, Gou L, Zhu Z, Cheng L, Ren B.   +16 more
europepmc   +1 more source

Bacteriophage T4 regA protein. Purification of a translational repressor.

, 1985
Eric S. Miller, Robert B. Winter, Kristine M. Campbell, Scott Power, Larry Gold   +4 more
openalex   +1 more source

l-Glutamine Represses the Unfolded Protein Response in the Small Intestine of Weanling Piglets [PDF]

, 2019
Yu He, Xiaoxiao Fan, Ning Liu, Qingqing Song, Jiao Kou, Yahui Shi, Xuan Luo, Zhaolai Dai, Ying Yang, Zhenlong Wu, Guoyao Wu   +10 more
openalex   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Supplementary Table 1 from Hepatitis B Virus X Protein Represses Expression of Tumor Suppressor PTPN18 in Hepatocellular Carcinoma

Zhenyu Zhou, Wei Yu, Huoming Li, Juanyi Shi, Shiyu Meng, Yongcong Yan, Ruibin Chen, Haohan Liu, Jie Wang, Jian Sun, Zhiyu Xiao, Jianlong Zhang   +11 more
openalex   +1 more source

Zinc finger protein ZBTB20 promotes toll-like receptor-triggered innate immune responses by repressing IκBα gene transcription [PDF]

, 2013
Xingguang Liu, Peng Zhang, Yan Bao, Yanmei Han, Yan Wang, Qian Zhang, Zhenzhen Zhan, Jun Meng, Yingke Li, Nan Li, Weiping J. Zhang, Xuetao Cao   +11 more
openalex   +1 more source

Thecl repressor of bacteriophage P1 operator-repressor interaction of wild-type and mutant repressor proteins

Nucleic Acids Research, 1989
Jochen Hemrich, Hans-Dieter Riedel, Barbara R. Baumstark, Makoto Kimura, Heinz Suhuster   +4 more
openaire   +2 more sources