Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The Signal and the Noise: The Problem of Reproducibility
, 2016 Cameron Neylon
openalex +1 more source
Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT With or Without Correction of Ocular Rotation [PDF]
, 2013 Hiroyo Hirasawa +12 more
openalex +1 more source
A Reproducible and Reusable Pipeline for Segmentation of Geoscientific Imagery
, 2022 Daniel Buscombe, Evan B. Goldstein
openalex +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Highly reproducible SERS substrate based on polarization-free Ag nanoparticles decorated SiO2/Si core-shell nanowires array [PDF]
, 2015 Xiaoying Liu +4 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
International Journal of Communication, 2019 Computational communication science (CCS) offers an opportunity to accelerate the scope and pace of discovery in communication research. This article argues that CCS will profit from adopting open science practices by fostering the reusability of data ...
Wouter van Atteveldt +3 more
doaj
Accurate and Reproducible Gene Expression Profiles from Laser Capture Microdissection, Transcript Amplification, and High Density Oligonucleotide Microarray Analysis [PDF]
, 2003 Verónica Luzzi +4 more
openalex +1 more source