Results 121 to 130 of about 690,617 (311)
Can we Trust Chatbots for now? Accuracy, reproducibility, traceability; a Case Study on Leonardo da Vinci's Contribution to Astronomy [PDF]
, 2023 Didier El Baz
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FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Reproducibility of Her2/neu scoring in gastric cancer and assessment of the 10% cut‐off rule [PDF]
, 2014 Hans‐Michael Behrens +12 more
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Editorial for “Evaluation of the Reproducibility of MR Elastography Measurements of the Lumbar Back Muscles” [PDF]
, 2023 Paolo Spinnato
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FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source