Results 11 to 20 of about 743,359 (233)

Genetic Regulation of Physiological Reproductive Lifespan and Female Fertility [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
There is substantial genetic variation for common traits associated with reproductive lifespan and for common diseases influencing female fertility. Progress in high-throughput sequencing and genome-wide association studies (GWAS) have transformed our ...
Grant W. Montgomery   +2 more
exaly   +4 more sources

The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata). [PDF]

open access: yesPLoS Biology, 2006
The study of post-reproductive lifespan has been of interest primarily with regard to the extended post-menopausal lifespan seen in humans. This unusual feature of human demography has been hypothesized to have evolved because of the "grandmother" effect,
David Reznick   +2 more
doaj   +3 more sources

The Effect of Post-Reproductive Lifespan on the Fixation Probability of Beneficial Mutations. [PDF]

open access: yesPLoS ONE, 2015
Post-reproductive lifespan is a common trait among mammals and is usually considered to be neutral; i.e. with no influence on population dynamics. Here, we explore the role of post-reproductive lifespan in the fixation probability of beneficial genetic ...
Stefano Giaimo, Annette Baudisch
doaj   +2 more sources

Reproductive capability is associated with lifespan and cause of death in companion dogs. [PDF]

open access: yesPLoS ONE, 2013
Reproduction is a risky affair; a lifespan cost of maintaining reproductive capability, and of reproduction itself, has been demonstrated in a wide range of animal species.
Jessica M Hoffman   +2 more
doaj   +2 more sources

Reproductive history and cardiometabolic disease: the role of endogenous estrogen exposure across the lifespan in postmenopausal women

open access: yesBMC Women's Health
Background The association between cumulative endogenous estrogen exposure across the lifespan, especially considering reproductive events, and women’s cardiometabolic health remain unclear.
Yingze Zhu   +10 more
doaj   +2 more sources

Post-Reproductive Lifespan in Wild Mountain Gorillas [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America
Martha M. Robbins, Nikolaos Smit
exaly   +2 more sources

Reproductive cessation and post-reproductive lifespan in Asian elephants and pre-industrial humans [PDF]

open access: yes, 2022
Conclusions: Our results show that the reproductive and survival patterns of Asian elephants differ from other long-lived animals exhibiting menopause, such as humans, and extreme longevity alone does not promote the evolution of menopause or post ...
Virpi Lummaa   +2 more
core   +1 more source

Gene pathways that delay Caenorhabditis elegans reproductive senescence. [PDF]

open access: yesPLoS Genetics, 2014
Reproductive senescence is a hallmark of aging. The molecular mechanisms regulating reproductive senescence and its association with the aging of somatic cells remain poorly understood.
Meng C Wang   +4 more
doaj   +1 more source

Reproductive-dependent effects of B vitamin deficiency on lifespan and physiology

open access: yesFrontiers in Nutrition, 2023
B vitamins constitute essential micronutrients in animal organisms, executing crucial roles in numerous biological processes. B vitamin deficiency can result in severe health consequences, including the impairment of reproductive functions and increased ...
Guixiang Yu   +4 more
doaj   +1 more source

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