Results 1 to 10 of about 223,319 (331)

Promoting Drp1-Mediated Mitochondrial Division in Nickel Nanoparticles-Induced Reproductive Toxicity in GC-2 Cells [PDF]

Nanomaterials
Male reproductive disorders and declining fertility rates play an important role in birth rates, and their impact on future populations makes them one of the most serious public health issues of this century.
Liya Qiao, Zhimin Tong, Yabing Xu, Chunliu Guan, Geyu Liang, Lu Kong   +5 more
doaj   +2 more sources

Reproductive toxicity of micro- and nanoplastics

Environment International, 2023
Large-scale plastic pollution occurs in terrestrial and marine environments and degrades into microparticles (MP) and nanoparticles (NP) of plastic. Micro/nanoplastics (MP/NPs) are found throughout the environment and different kinds of marine organisms ...
Shaolong Yang, Mengzhen Li, Richard Yuen Chong Kong, Lei Li, Rong Li, Jian Chen, Keng Po Lai   +6 more
doaj   +2 more sources

Oral repeated-dose systemic and reproductive toxicity of 6:2 fluorotelomer alcohol in mice

Toxicology Reports, 2015
6:2 fluorotelomer alcohol (6:2 FTOH) was evaluated for potential systemic repeated-dose and reproductive toxicity in mice. 6:2 FTOH was administered by oral gavage to CD-1 mice as a suspension in 0.5% aqueous methylcellulose with 0.1% Tween-80 at dosages
Pushkor Mukerji, Jessica Caverly Rae, Robert C. Buck, John C. O’Connor   +3 more
doaj   +2 more sources

Convenient screening of the reproductive toxicity of favipiravir and antiviral drugs in Caenorhabditis elegans [PDF]

Heliyon
Reproductive toxicity is one of the major concerns in drug development. Thus, we have developed its screening system using Caenorhabditis elegans, which has a life cycle of three days and similar coding genes as humans.
Kimiyasu Shiraki, Mizuki Mishima, Noriaki Sato, Yasuo Imoto, Kiyoji Nishiwaki   +4 more
doaj   +2 more sources

Machine learning models for rat multigeneration reproductive toxicity prediction

Frontiers in Pharmacology, 2022
Reproductive toxicity is one of the prominent endpoints in the risk assessment of environmental and industrial chemicals. Due to the complexity of the reproductive system, traditional reproductive toxicity testing in animals, especially guideline ...
Jie Liu, Wenjing Guo, Fan Dong, Jason Aungst, Suzanne Fitzpatrick, Tucker A. Patterson, Huixiao Hong   +6 more
doaj   +1 more source

A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans

Hygiene and Environmental Health Advances, 2022
The release of several environmental pollutants poses a potential threat to the several ecosystems and humans. Reproductive toxicity represents one of the most significant toxic effects of environmental contaminants.
Yunjiang Yu, Haibo Chen, Xin Hua, Chen Wang, Chenyin Dong, Dongli Xie, Shihui Tan, Mingdeng Xiang, Hui Li   +8 more
doaj   +1 more source

Effects of Decamethylcyclopentasiloxane on Reproductive Systems in Female Rats

Toxics, 2023
The female reproductive system becomes fertile through the action of hormones involved in the hypothalamic-pituitary-ovarian axis. On the other hand, estrogen-like endocrine disruptors released into the environment come into contact with humans by ...
Jimin Lee, Kangmin Kim, Seon-Mi Park, Jin-Sook Kwon, Eui-Bae Jeung   +4 more
doaj   +1 more source

Palliative effects of metformin on testicular damage induced by triptolide in male rats

Ecotoxicology and Environmental Safety, 2021
As a widely existing traditional Chinese medicine component, TP (triptolide) has serious reproductive toxicity which causes severe damage to the reproductive system and limits its application prospect. TP and MET (metformin) have shown great potential in
Ke Wang, Huina Hu, Wenbo Cui, Xuelian Zhang, Qi Tang, Nuan Liu, Xianyong Lan, Chuanying Pan   +7 more
doaj   +1 more source

Paternal DEHP Exposure Triggers Reproductive Toxicity in Offspring via Epigenetic Modification of H3K27me3. [PDF]

Toxics
Zhang L, Yang R, Xu G, Wang L, Chen W, Tan Y, Zhang G, Liu W, Zhang G, Li J, Zhou Z.   +10 more
europepmc   +3 more sources

Follicular phase length has no influence on frozen-thawed embryo transfers in natural cycles

Journal of Ovarian Research, 2020
Background Whether menstrual variability in women with regular and ovulatory cycle could affect embryo implantation remains controversial, with conflicting evidences presented in the literature.
Ying Ying, Fuman Qiu, Qing Huang, Sichen Li, Haiying Liu, Jianqiao Liu   +5 more
doaj   +1 more source