Results 21 to 30 of about 219,005 (309)

Hexabromocyclododecane and hexachlorocyclohexane: How lessons learnt have led to improved regulation [PDF]

, 2014
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2014 Taylor & Francis.The use of chemicals by society has many benefits but contamination of the environment is an unintended consequence.
BSEF, Cyril O. Onogbosele, Desjardins D., Drottar K.R., Drottar K.R., EC, Hunziker R.W., IPCS, IPCS, Law K., Mackay D., Mark D. Scrimshaw, Roberts C.A., Swedish Chemicals Agency, WHO   +14 more
core   +1 more source

Establishment Methods and Application Evaluation of Animal Models in Reproductive Toxicology Research

Shiyan dongwu yu bijiao yixue
Reproductive toxicology is a discipline that uses toxicological methods to study the mechanisms by which foreign substances interfere with the generation of eggs or sperm and their detrimental effects on offspring.
HUANG Dongyan, WU Jianhui
doaj   +1 more source

Review of QSAR Models and Software Tools for Predicting Developmental and Reproductive Toxicity [PDF]

, 2010
This report provides a state-of-the-art review of available computational models for developmental and reproductive toxicity, including Quantitative Structure-Activity Relationship (QSARs) and related estimation methods such as decision tree approaches ...
LO PIPARO ELENA, WORTH Andrew
core   +1 more source

Development, validation and application of ERα- and PPARγ-mediated female reproductive toxicity prediction models based on adverse outcome pathway

Ecotoxicology and Environmental Safety
Traditional methods for reproductive toxicity assessment are insufficient for high-throughput chemical screening. Although efforts have been made in recent years to develop predictive models for reproductive toxicity, in-depth modeling of female-specific
Ya Tian, Liang Lyu, Hui-ming Yang, Yi Yang, Zheng Li, Yi-yuan Zeng, Hong-zhan Liu, Li-li Yang, Xiao-feng Zhang   +8 more
doaj   +1 more source

Is there a causal association between genotoxicity and the imposex effect? [PDF]

, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger, Michael H. Depledge, Jörg Oehlmann, Susan Jobling, Tamara S. Galloway, Colborn T, Collins MKL, Cooke H, Depledge MH, Gibbs PE, Harring KE, Harris JO, Laruelle F, Smith BS   +13 more
core   +1 more source

Research progress on food-derived antioxidants for alleviating toxicity of endocrine disrupting chemicals

环境与职业医学
Endocrine disrupting chemicals (EDCs) are a class of chemical substances widely present in daily-life environment, and can enter human body through various pathways, posing a threat to reproductive development and health.
Jiaxian CHEN, Maohua MIAO, Ziliang WANG
doaj   +1 more source

Impact of Endosulfan on Male Reproductive functions - a review [PDF]

Perspectives In Medical Research, 2016
Endosulfan is an organochlorine insecticide and acaracide used to control a broad range of insect and arthropod pests on a wide variety of crops in many agrosystems. It can cause acute and chronic toxicity.
Srinivasa Jayachandra
doaj  

The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review

Ecotoxicology and Environmental Safety, 2023
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark. Exposure to arsenic reduces sperm count, impairs fertilization, and causes
Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan   +1 more
doaj   +1 more source

Molecular Targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) within the Zebrafish Ovary: Insights into TCDD-induced Endocrine Disruption and Reproductive Toxicity [PDF]

, 2008
TCDD is a reproductive toxicant and endocrine disruptor, yet the mechanisms by which it causes these reproductive alterations are not fully understood.
Carvan, Michael J., III, Hessner, Martin J., Hutz, Reinhold J., King Heiden, Tisha C., Rise, Matthew L., Struble, Craig   +5 more
core   +1 more source

Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats [PDF]

, 2006
Pregnant Sprague–Dawley rats were exposed to ethylbenzene (EB; 0, 250, or 1000 ppm) and methylethylketone (MEK; 0, 1000, or 3000 ppm), alone and in combination, by inhalation, for 6 h/day, during days 6–20 of gestation.
Bourges-Abella, Nathalie, Cadot, R., Gallissot, Frédéric, Lambert, A.M., Morel, G., Sabaté, Jean-Philippe, Saillenfait, Anne-Marie   +6 more
core   +1 more source