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Reprogramming chromatin

Critical Reviews in Biochemistry and Molecular Biology, 2012
Cellular reprogramming involves the artificial dedifferentiation of somatic cells to a pluripotent state. When affected by overexpressing specific transcription factors, the process is highly inefficient, as only 0.1-1% of cells typically undergo the transformation.
Ehrensberger AH, Svejstrup JQ
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Reprogramming to resist

Science, 2017
Prostate cancer cells alter identity to resist ...
Steven P. Balk, Kathleen Kelly
openaire   +3 more sources

Regeneration and reprogramming

Current Opinion in Genetics & Development, 2012
Recent reprogramming studies indicate that mammalian, somatic cells have the potential to achieve pluripotent states and undergo cell type switching. Such cellular traits are observed under natural conditions in animals that regenerate complex organs. A number of invertebrates display the amazing trait of whole body regeneration.
Dunja Knapp, Elly M. Tanaka
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Cell reprogramming

Current Opinion in Genetics & Development, 2012
C5 - Other Refereed Contribution to Refereed ...
Pera, MF, Plath, K
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A reprogramming machine

Communications of the ACM, 1966
In this paper a description is given of a model programming system which is directed by a programming language and has a library for storing the user's items. Rules are given for transforming programs written in the language and for rearranging the items in the library so that they share their common parts.
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Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice

Science, 2021
Description Pluripotency factor drives cardiogenesis Research indicates that the adult mammalian heart does not contain cardiac stem cells and the vast majority of cardiomyocytes do not divide. Heart regeneration is thus limited after injury.
Yanpu Chen   +8 more
semanticscholar   +1 more source

The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression

International Journal of Radiation Biology, 2019
In the early 1920s, Warburg published experimental data on the enhanced conversion of glucose to pyruvate (followed by lactate formation) even in the presence of abundant oxygen (aerobic glycolysis, Warburg effect).
P. Vaupel, H. Schmidberger, A. Mayer
semanticscholar   +1 more source

Reprogramming in nuclear transfer

Current Opinion in Genetics & Development, 2003
Reprogramming a nucleus by transferring it to oocyte cytoplasm triggers epigenetic changes that eventually lead to the restoration of a totipotent state and the birth of a viable animal. A simplified way of studying this complex process is to study cell hybrids.
Jouneau, Alice, Renard, Jean Paul
openaire   +4 more sources

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