Results 41 to 50 of about 403,028 (282)
miRNA-based rapid differentiation of purified neurons from hPSCs advancestowards quick screening for neuronal disease phenotypes in vitro [PDF]
, 2020 Obtaining differentiated cells with high physiological functions by an efficient, but simple and rapid differentiation method is crucial for modeling neuronal diseases in vitro using human pluripotent stem cells (hPSCs).
Aoyama, Takeshi +10 more
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Macrophage Polarization and Reprogramming in Acute Inflammation: A Redox Perspective
Antioxidants, 2022 Macrophage polarization refers to the process by which macrophages can produce two distinct functional phenotypes: M1 or M2. The balance between both strongly affects the progression of inflammatory disorders.
S. Pérez, Sergio Rius-Pérez
semanticscholar +1 more source
Stem Cell Research, 2014 Despite advances in the field of somatic cell reprogramming, an understanding and exploration of the underlying mechanisms governing this process are only recently emerging. It is now increasingly apparent that key sequential events correlate with the reprogramming process; a process previously thought to be random and unpredictable is now looking, to ...
Laurent David +3 more
openaire +4 more sources
Direct Cardiac Reprogramming: Progress and Promise. [PDF]
, 2018 The human adult heart lacks a robust endogenous repair mechanism to fully restore cardiac function after insult; thus, the ability to regenerate and repair the injured myocardium remains a top priority in treating heart failure.
Ardehali, Reza, Engel, James L
core +3 more sources
The Journal of Cell Biology, 2004 Does the Kaposi sarcoma (KS) herpesvirus (KSHV) replicate in lymphatic endothelial cells (LECs) or blood vascular endothelial cells (BECs)? Two groups have come up with a surprising answer to this question: neither. Instead the oncogenic virus modifies both of the two cell types to an intermediate state that better suits the virus' replicative needs.
William A. Wells
openalex +4 more sources
Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis [PDF]
, 2019 © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Xu, X., Li, G., Li, C., Zhang, J., Wang, Q., Simmons, D. K., Chen, X., Wijesena, N., Zhu, W., Wang, Z.,
Aluru, Neelakanteswar +20 more
core +2 more sources
Strategies for in vivo reprogramming [PDF]
Current Opinion in Cell Biology, 2019 Reprogramming has the potential to provide specific cell types for regenerative medicine applications aiming at replacing tissues that have been lost or damaged due to degenerative diseases and injury. In this review we discuss the latest strategies and advances of in vivo reprogramming to convert cell identities in living organisms, including ...
Ofenbauer, Andreas, Tursun, Baris
openaire +3 more sources
Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation [PDF]
, 2018 Retinitis pigmentosa (RP) is an inherited retinal degenerative disease. Mutations in EYS have been associated with autosomal recessive RP. The human iPS cell line, CABi002-A, derived from peripheral blood mononuclear cells from a patient carrying a ...
Bhattacharya, Shomi S. +5 more
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Cell Communication and Signaling, 2022 Metabolic reprogramming and immune escape play a major role in tumorigenesis. Increasing number of studies have shown that reprogramming of glutamine metabolism is a putative determinant of the anti-tumor immune response in the tumor microenvironment ...
Guofeng Ma +10 more
semanticscholar +1 more source
Scientific Reports, 2022 Drosophila melanogaster tumor models are growing in popularity, driven by the high degree of genetic as well as functional conservation to humans. The most common method to measure the effects of a tumor on distant organs of a human cancer patient is to ...
Petter Holland +4 more
doaj +1 more source