Results 41 to 50 of about 338,803 (187)
A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]
open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...
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Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals
Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon +13 more
doaj +1 more source
Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]
It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J +7 more
core +4 more sources
Five decades of nuclear transfer (NT) experiments have established a key principle in developmental genetics - despite vast functional differences, virtually all of the cells in an adult organism maintain an identical genome 1. Studies in several species have shown that the nucleus of a differentiated cell can be reprogrammed by exposure to egg ...
Suneet, Agarwal, George Q, Daley
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Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer [PDF]
York University ...
Bhattacharya, Debasmita, Scimè, Anthony
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Flexible Sensor Network Reprogramming for Logistics [PDF]
Besides the currently realized applications, Wireless Sensor Networks can be put to use in logistics processes. However, doing so requires a level of flexibility and safety not provided by the current WSN software platforms.
Evers, L., Havinga, P.J.M., Kuper, J.
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Ribonucleic acid interference (RNAi) based on microRNA (miRNA) may provide efficient and safe therapeutic opportunities. However, natural microRNAs can not easily be regulated and usually cause few phenotypic changes.
Yonghao Zhan +11 more
doaj +1 more source
Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park +5 more
doaj +1 more source
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI [PDF]
Background: Global epigenetic reprogramming is considered to be essential during embryo development to establish totipotency. In the classic model first described in the mouse, the genome-wide DNA demethylation is asymmetric between the paternal and the ...
De Schauwer, Catharina +3 more
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Direct reprogramming 101 [PDF]
Direct reprogramming of somatic cells into a pluripotent state has been achieved with a set of just four transcription factors. Many scientists and medical doctors are trying to elucidate the causes of intractable diseases and discover new drugs using the newest types of technology.
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