Results 41 to 50 of about 338,803 (187)

A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]

open access: yes, 2018
open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...

core   +1 more source

Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

open access: yesGenome Biology, 2021
Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon   +13 more
doaj   +1 more source

Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]

open access: yes, 2012
It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J   +7 more
core   +4 more sources

AID for reprogramming [PDF]

open access: yesCell Research, 2010
Five decades of nuclear transfer (NT) experiments have established a key principle in developmental genetics - despite vast functional differences, virtually all of the cells in an adult organism maintain an identical genome 1. Studies in several species have shown that the nucleus of a differentiated cell can be reprogrammed by exposure to egg ...
Suneet, Agarwal, George Q, Daley
openaire   +2 more sources

Flexible Sensor Network Reprogramming for Logistics [PDF]

open access: yes, 2007
Besides the currently realized applications, Wireless Sensor Networks can be put to use in logistics processes. However, doing so requires a level of flexibility and safety not provided by the current WSN software platforms.
Evers, L., Havinga, P.J.M., Kuper, J.
core   +7 more sources

Synthetic Tet-inducible artificial microRNAs targeting β-catenin or HIF-1α inhibit malignant phenotypes of bladder cancer cells T24 and 5637

open access: yesScientific Reports, 2015
Ribonucleic acid interference (RNAi) based on microRNA (miRNA) may provide efficient and safe therapeutic opportunities. However, natural microRNAs can not easily be regulated and usually cause few phenotypic changes.
Yonghao Zhan   +11 more
doaj   +1 more source

Anti-Cancer Effects of Lactobacillus plantarum L-14 Cell-Free Extract on Human Malignant Melanoma A375 Cells

open access: yesMolecules, 2020
Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park   +5 more
doaj   +1 more source

Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI [PDF]

open access: yes, 2017
Background: Global epigenetic reprogramming is considered to be essential during embryo development to establish totipotency. In the classic model first described in the mouse, the genome-wide DNA demethylation is asymmetric between the paternal and the ...
De Schauwer, Catharina   +3 more
core   +1 more source

Direct reprogramming 101 [PDF]

open access: yesDevelopment, Growth & Differentiation, 2010
Direct reprogramming of somatic cells into a pluripotent state has been achieved with a set of just four transcription factors. Many scientists and medical doctors are trying to elucidate the causes of intractable diseases and discover new drugs using the newest types of technology.
openaire   +2 more sources

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