Results 61 to 70 of about 403,028 (282)

Epigenetic impairments in development of parthenogenetic preimplantation mouse embryos

The Journal of Reproduction and Development, 2018
Parthenogenesis is an activation process of oocytes that occur without the participation of sperm. Evidence suggests that normal development of embryos requires proper expression of several imprinted genes inherited from both the paternal and maternal ...
Ngan Thi Kim HO, Thuy Van Thi NGUYEN, Thuan Van NGUYEN, Hong-Thuy BUI   +3 more
doaj   +1 more source

Enzymatic isolation of porcine preantral follicles impairs oocyte viability and long-term in vitro growth

The Journal of Reproduction and Development
The enzymatic isolation of preantral follicles (PAFs) is considered the most efficient method for retrieving a large number of intact follicles, offering significant advantages in terms of yield and processing time.
Ba Anh My LE, Lien Boi Linh NGUYEN, Phuong Thanh NGUYEN, Ha Nhat Lam VO, Ngoc Song Thu TRAN, Bao Nghi TRAN, Ngoc Thao Vy NGUYEN, Chi Thien LAM, Nhat-Thinh NGUYEN, Van Thuan NGUYEN, Hong-Thuy BUI   +10 more
doaj   +1 more source

Isolation of female germline stem cells from porcine ovarian tissue and differentiation into oocyte-like cells

The Journal of Reproduction and Development, 2019
Historically, it had been widely accepted that the female mammalian ovary contained a limited number of oocytes that would reduce over time, without the possibility of replenishment. However, recent studies have suggested that female germline stem cells (
Huy-Hoang NGUYEN, Bui Le Quynh NHU, Nguyen Nhat Phuong UYEN, Van-Thuan NGUYEN, Hong-Thuy BUI   +4 more
doaj   +1 more source

Autophagosome Biogenesis

Cells, 2023
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and protects cells from potentially harmful agents that may accumulate in the cytoplasm, including pathogens, protein aggregates, and dysfunctional organelles ...
Yan Zhen, Harald Stenmark
doaj   +1 more source

Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]

, 2017
In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core   +1 more source

Deterministic reprogramming of neutrophils within tumors

Science
Neutrophils are increasingly recognized as key players in the tumor immune response and are associated with poor clinical outcomes. Despite recent advances characterizing the diversity of neutrophil states in cancer, common trajectories and mechanisms ...
M. Ng, Immanuel Kwok, Leonard Tan, Changming Shi, Daniela Cerezo-Wallis, Yingrou Tan, K. Leong, Gabriel F. Calvo, Katharine Yang, Yuning Zhang, Jingsi Jin, K. Liong, Dandan Wu, Rui He, Dehua Liu, Ye Chean Teh, Camille Blériot, N. Caronni, Zhaoyuan Liu, Kaibo Duan, V. Narang, Iván Ballesteros, Federica Moalli, Mengwei Li, Jinmiao Chen, Yao Liu, Lianxin Liu, Jingjing Qi, Yingbin Liu, Lingxi Jiang, Baiyong Shen, Hui Cheng, T. Cheng, Veronique Angeli, Ankur Sharma, Y. Loh, H. Tey, Shu Zhen Chong, M. Iannacone, R. Ostuni, Andrés Hidalgo, F. Ginhoux, L. Ng   +42 more
semanticscholar   +1 more source

Improving porcine in vitro blastocyst development using fetal bovine serum, amino acids, and insulin-transferrin-selenium

The Journal of Reproduction and Development
In vitro production of porcine-hatched blastocysts is important for various applications. However, the mechanobiology of blastocoel expansion and hatching remains poorly understood.
Ba Anh My LE, Lien Boi Linh NGUYEN, Chi Thien LAM, Nhat-Thinh NGUYEN, Ngoc Thao Vy NGUYEN, Van Thuan NGUYEN, Hong-Thuy BUI   +6 more
doaj   +1 more source

High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues

Antioxidants, 2021
Extracellular vesicles (EVs) are paracrine factors that mediate stem cell therapeutics. We aimed at evaluating the possible therapeutic and esthetic applications of EVs prepared from the waste human facial tissue-derived orbicularis oculi muscle stem ...
Kyung Min Lim, Ahmed Abdal Dayem, Yujin Choi, Yoonjoo Lee, Jongyub An, Minchan Gil, Soobin Lee, Hee Jeong Kwak, Balachandar Vellingirl, Hyun Jin Shin, Ssang-Goo Cho   +10 more
doaj   +1 more source

Molecular and Genetic Determinants of Glioma Cell Invasion. [PDF]

, 2017
A diffusely invasive nature is a major obstacle in treating a malignant brain tumor, "diffuse glioma", which prevents neurooncologists from surgically removing the tumor cells even in combination with chemotherapy and radiation.
Kato, Yoichiro, Masui, Kenta, Mischel, Paul S, Sawada, Tatsuo, Shibata, Noriyuki   +4 more
core   +2 more sources

Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

Signal Transduction and Targeted Therapy, 2020
Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy demands.
Enli Yang, Xuan Wang, Z. Gong, Mia Yu, Haiwei Wu, Dongsheng Zhang   +5 more
semanticscholar   +1 more source