Results 171 to 180 of about 1,301,492 (295)

How European Research Projects Can Support Vaccination Strategies: The Case of the ORCHESTRA Project for SARS-CoV-2. [PDF]

Vaccines (Basel), 2023
Azzini AM, Canziani LM, Davis RJ, Mirandola M, Hoelscher M, Meyer L, Laouénan C, Giannella M, Rodríguez-Baño J, Boffetta P, Mates D, Malhotra-Kumar S, Scipione G, Stellmach C, Rinaldi E, Hasenauer J, Tacconelli E.   +16 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Managing linguistic obstacles in multidisciplinary, multinational, and multilingual research projects. [PDF]

PLoS One
Specht A, Stall S, Machicao J, Catry T, Chaumont M, David R, Devillers R, Edmunds R, Jarry R, Mabile L, Miyairi N, O'Brien M, Correa PP, Santos S, Subsol G, Wyborn L.   +15 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Characterizing redundancy in pharmacy residency research projects. [PDF]

Am J Health Syst Pharm
Yeager LS, Behal M, Flannery AH, Ali D, Livingston J, Woodward B, Cook AM.   +6 more
europepmc   +1 more source

Describing the Breadth and Scope of Keck Medical Student Primary Care Research Projects. [PDF]

PRiMER, 2022
Reilly JM, Robinson J, Kogan AC, Greenberg I.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Mandatory research projects during medical specialist training in Australia and New Zealand: a survey of trainees' experiences and reports. [PDF]

Med J Aust
Stehlik P, Withers C, Bourke RC, Barnett AG, Brandenburg C, Noble C, Bannach-Brown A, Keijzers GB, Scott IA, Glasziou PP, Veysey EC, Mickan S, Morgan M, Joshi H, Forrest K, Campbell TG, Henry DA.   +16 more
europepmc   +1 more source

Small molecule biomarker discovery: Proposed workflow for LC-MS-based clinical research projects. [PDF]

J Mass Spectrom Adv Clin Lab, 2023
Rischke S, Hahnefeld L, Burla B, Behrens F, Gurke R, Garrett TJ.   +5 more
europepmc   +1 more source

Analyses in Biology: an analytical alternative to traditional research projects [PDF]

, 2008
James, HA
core