Results 131 to 140 of about 19,550,098 (273)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Research and development prospects of TRIM65. [PDF]

J Cancer Res Clin Oncol
Deng NH, Chen JH, Tian Z, Quan SB.
europepmc   +1 more source

Research and researcher development

Research and researcher development training seminar for ESR ...
openaire   +1 more source

Research and development in Hungary [PDF]

, 2002
Research and Development Division, Ministry of Education, Hungary
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Development and application of artificial intelligence in traditional Chinese medicine research and development. [PDF]

Chin Med
Wang A, Luo Q, Tan X, Yao Y, Peng X, Luo H, Hu Y.   +6 more
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The collaborations among healthcare systems, research institutions, and industry on artificial intelligence research and development. [PDF]

Front Artif Intell
Ye J, Ma M, Abuhashish M.
europepmc   +1 more source

Biological reviews of important Cambodian fish species, based on fishbase 2004 Volume 1 [PDF]

This document is a review of all the information published worldwide about ten fish species that contribute significantly to Cambodian fishery resources.Freshwater fish, Cambodia, Channa striata, Channa micropeltes, Barbonymus altus, Barbonymus ...
Baran, E., Chheng Phen, Inland Fisheries Research and Development Institute, Leng Sy Vann, Touch Bun Thang, WorldFish Center   +5 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source