Results 91 to 100 of about 34,823,597 (367)
Research Design Considerations [PDF]
Journal of Graduate Medical Education, 2016 ‘‘I’d really like to do a survey’’ or ‘‘Let’s conduct some interviews’’ might sound like reasonable starting points for a research project. However, it is crucial that researchers examine their philosophical assumptions and those underpinning their research questions before selecting data collection methods. Philosophical assumptions relate to ontology,
Laura Nimmon +4 more
openaire +3 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Exploring the Future of Remote User Research [PDF]
arXiv, 2022 The rapid move to remote work due to COVID-19 social distancing policies has slowed or stopped most in-person qualitative user research activities. The limitation on in-person activities has pushed many user researchers to consider how they can continue their research remotely and presents an opportunity for user research teams to (re)design their ...
arxiv
Architectural Research Quarterly, 2017 Early issues of arq in the mid-1990s were preoccupied with the possibilities for researching architecture through design: how design research might be constituted and communicated, and – practically for architecture schools at that time – how design might be counted as research in the newly-introduced metrics used to judge research quality in UK ...
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Politics and Governance, 2013 The vast literature on party identification has gradually become bogged down by disputes about how to interpret observational data. This paper proposes the use of experimental designs to shed light on the responsiveness of party identification to short ...
Donald P. Green
doaj +1 more source
Design research, eHealth, and the convergence revolution [PDF]
arXiv, 2019 The Quadruple Aim is a framework which prioritizes four aims, or dimensions of performance, for innovating in the healthcare domain, respectively: 1) enhancing the individual experience of care; 2) improving the work life of health care clinicians and staff; 3) improving the health of populations; and 4) reducing the per capita cost of care.
arxiv
Advancing service design research with design science research
Journal of Service Management, 2019 Purpose Service design is a multidisciplinary approach that is key to service innovation, as it brings new service ideas to life. In this context, the development of new service design methods and models for creating new service futures is an important stream of service design research.
Teixeira, Jorge Grenha +2 more
openaire +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source