Results 71 to 80 of about 67,932,399 (174)

Reward processing in children with affective dysregulation

JCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner, Francisca Giller, Nathalie Holz, Anna Kaiser, Christine Igel, Sarah Hohmann, Manfred Döpfner, Veit Roessner, Christian Beste, Tobias Banaschewski, Daniel Brandeis, on behalf ofthe ADOPT Consortium   +11 more
wiley   +1 more source

Understanding the associations between neurodevelopmental features and internalising and externalising behaviours: A transdiagnostic approach

JCPP Advances, EarlyView.
Abstract Background Internalising and externalising behaviours—significant markers for lifetime psychiatric vulnerability—are elevated in children with neurodevelopmental diagnoses, including autism. Although neurodevelopmental features of autism are dimensions that span the population, limited research has examined their differential patterns of ...
Sarah J. Carrington, Jennifer Keating, Mirko Uljarević, Kirsten Abbot‐Smith, Catherine R. G. Jones, Susan R. Leekam   +5 more
wiley   +1 more source

Evolving Concepts of the Schizophrenia Spectrum: A Research Domain Criteria Perspective

Frontiers in Psychiatry, 2021
Several trends intersecting over the past two decades have generated increasing debate as to how the concepts of schizophrenia, the schizophrenia spectrum, and the psychotic disorders spectrum should be regarded.
Bruce N. Cuthbert, Sarah E. Morris
doaj   +1 more source

A new approach to assessment for young children referred by education professionals for socio‐emotional, behavioural, and cognitive difficulties

JCPP Advances, EarlyView.
Abstract Background Young children with emerging mental health problems and neurodevelopmental differences often do not receive the support they need early in life, and if they do receive support, it may not be appropriately targeted towards their individual needs.
Amy L. Paine, Steve Eaton, Aikaterini Bekiropoulou, Christopher Hobson, Cerith Waters, Anita Thapar, Katherine H. Shelton, Kate Langley, Catherine R. G. Jones, Dale F. Hay, Susan R. Leekam, Elisabeth von dem Hagen, The Neurodevelopment Assessment Unit Team, Stephanie H. M. van Goozen   +13 more
wiley   +1 more source

Dimensional clinical phenotyping using post‐mortem brain donor medical records: post‐mortem RDoC profiling is associated with Alzheimer's disease neuropathology

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023
Introduction Transdiagnostic dimensional phenotypes are essential to investigate the relationship between continuous symptom dimensions and pathological changes.
Jonathan Vogelgsang, Shu Dan, Anna P. Lally, Michael Chatigny, Sangeetha Vempati, Joshua Abston, Peter T. Durning, Derek H. Oakley, Thomas H. McCoy, Torsten Klengel, Sabina Berretta   +10 more
doaj   +1 more source

Editorial: Transdiagnostic approaches to child and adolescent mental health—Integrating development, dimensions, and mechanisms

JCPP Advances, EarlyView.
Abstract Co‐occurrence of child and adolescent neurodevelopmental and mental health conditions is the rule rather than the exception, yet translating this insight into shared frameworks and clinical practice remains challenging. In this Editorial, we are pleased to introduce the 26 papers included in the 2026 Special Issue of JCPP Advances.
Alessio Bellato, Stephen P. Becker, Catharina A. Hartman, Henrik Larsson, James J. Li, Samantha J. Lynch, Giorgia Michelini   +6 more
wiley   +1 more source

Enhancing post-traumatic stress disorder patient assessment: leveraging natural language processing for research of domain criteria identification using electronic medical records

BMC Medical Informatics and Decision Making
Background Extracting research of domain criteria (RDoC) from high-risk populations like those with post-traumatic stress disorder (PTSD) is crucial for positive mental health improvements and policy enhancements.
Oshin Miranda, Sophie Marie Kiehl, Xiguang Qi, M. Daniel Brannock, Thomas Kosten, Neal David Ryan, Levent Kirisci, Yanshan Wang, LiRong Wang   +8 more
doaj   +1 more source

Longitudinal Sleep Spindle Maturation Trajectories and Their Association With Internalizing Problems in Adulthood

Journal of Sleep Research, EarlyView.
ABSTRACT Extensive cortical refinement from childhood to adulthood coincides with heightened vulnerability to internalizing problems, such as anxiety and depression. Thalamocortical sleep spindles may provide neurophysiological indices of such vulnerability.
Johanna Gfüllner, Kathrin Bothe, Michael A. Hahn, Christopher Höhn, Georg Gruber, Kerstin Hoedlmoser   +5 more
wiley   +1 more source

Can circadian rhythm predict changes in neurocognitive functioning in bipolar disorder: protocol of a 12-month longitudinal cohort study based on research domain criteria

Annals of Medicine, 2023
Introduction: Bipolar disorder (BD) is a prevalent and disabling mental disorder characterized by disrupted circadian rhythms and impaired neurocognitive features, both of which fall under the major domains of Research Domain Criteria (RDoC).
Huirong Luo, Xueqian Wang, Yinlin Zhang, Junyao Li, Renqin Hu, Zheng Zhang, Qian Liao, Xiaoxin Zhou, Wei Deng, Jian Yang, Qinghua Luo   +10 more
doaj   +1 more source

Transdiagnostic patterns of electroencephalography (EEG)‐derived aperiodic activity across schizophrenia‐spectrum, bipolar, and depressive disorders: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
Aperiodic electroencephalographic activity is proposed as a scalable marker of cortical population dynamics relevant to excitation–inhibition balance. However, it remains unclear whether aperiodic parameters represent disorder‐specific abnormalities or context‐sensitive indices of clinically relevant brain states.
Gia Han Le, Sabrina Wong, Sara Di Luch, Diana K. Orsini, Shreya Vasudeva, Sri Mahavir Agarwal, Cristian‐Daniel Llach, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source