Results 81 to 90 of about 26,805,984 (378)

Research Methodology in Global Strategy Research [PDF]

Global Strategy Journal, 2017
Research summaryWe review advances in research methodology used in global strategy research and provide suggestions on how researchers can improve their analyses and arguments. Methodological advances in the extraction of information, such as computer‐aided text analysis, and in the analysis of datasets, such as differences‐in‐differences and ...
Cuervo Cazurra, Alvaro, MUDAMBI, RAM, PEDERSEN, TORBEN, Piscitello, Lucia   +3 more
openaire   +5 more sources

Advancing Complexity Theory as a Qualitative Research Methodology

International Journal of Qualitative Methods, 2018
Although complexity theory is increasingly used to explain and understand complex health-system behavior, little is known about utilizing complexity theory to augment qualitative research methods. We advance this field by describing our use of complexity
Claire Gear, E. Eppel, J. Koziol-Mclain
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Research Methodology Through Writing Research Proposal Retrospectively by Combining Classroom Discussion and Collaborative Working Group in Lesson Study [PDF]

, 2015
Lesson Study (LS) was conducted aiming at: (1) describing the ideal steps in combining classroom discussion and collaborative working group in effort to improve students' comprehension on writing biology research proposal that is arranged retrospectively;
Hindun, I. (Iin), Husamah, H. (Husamah), Purwanti, E. (Ely), Rofieq, A. (Ainur), Wahyuni, S. (Sri)   +4 more
core  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Research methodology topics: Cross-sectional studies

Journal of Human Growth and Development, 2018
In health the most frequent researches are done in the form of observational studies. In this type of scientific research the researchers did not interfere with the phenomena under study, only observed in a systematic and standardized manner, collecting ...
J. Zangirolami-Raimundo, J. O. Echeimberg, C. Leone   +2 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Ethical Dilemmas in Qualitative Research Methodology: Researcher's Reflections.

, 2018
This article examines the ethical dilemmas that are specific to qualitative research methodology. These dilemmas concern the issues of withdrawal from the study, anonymity and confidentiality, which are discussed.
N. Ngozwana
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Exploring the IT usage in SMEs from New Zealand, Columbia and Chile using action-research methodology [PDF]

, 2012
The theory on the adoption and use of information technology (IT) in small and medium enterprises (SMEs) is abundant. However, methodologically speaking, action-research (AR) has been little explored as a method of construction of this theory, despite ...
Cataldo, Alejandro, McQueen, Robert J., Sepúlveda, Marcos   +2 more
core   +2 more sources