Results 101 to 110 of about 20,403,332 (296)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Prenatal exposure to medication and risk of childhood cancer – a systematic review and meta-analysis

open access: yesBMC Cancer
Background The use of medication during pregnancy carries a potential health risk, including childhood cancer, for the unborn child. However, most drugs examined in previous observational studies have shown inconsistent results with the risk of childhood
Alicia Lübtow   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mixed methods in health care research. Paradigms and philosphy [PDF]

open access: yes, 2018
When to use mixed methods is one of the most challenging issues that health care researchers currently face. The predominance of quantitative methods have not been enough to respond to many relevant questions on health care, that need a multiple approach.
Kendall, Sally
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Applying ethnographic methods to library research [PDF]

open access: yes, 2014
Bryony Ramsden of the University of Huddersfield explains why methods more commonly used in ethnography can be usefully applied to research in ...
Ramsden, Bryony
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

RESEARCH METHODS IN MARKETING [PDF]

open access: yes, 2011
Cornelissen, Christian Gabriel   +4 more
core   +2 more sources

Online research methods: An interview with Dr Neil Coulson [PDF]

open access: yes, 2014
Dr Neil Coulson, Associate Professor in Health Psychology at the University of Nottingham, is at the forefront of online research methods. His primary research explore the role of online support communities, online surveys, and the role of social ...
Williams, Sophie
core   +1 more source

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