Results 121 to 130 of about 6,667,826 (304)

PORCENTAJE DE COMPROMISO DE LESION CERVICAL DE ALTO GRADO Y PERSISTENCIA DE ENFERMEDAD RESIDUAL POSTCONO

Revista Chilena de Obstetricia y Ginecología, 2002
El objetivo de este trabajo fue evaluar la relación entre el porcentaje de cuello comprometido por neoplasia intraepitelial de alto grado en pacientes conizadas por asa leep y la persistencia de lesión residual en la pieza de histerectomía.
Fernando González C., Cayetano Napolitano R., Ricardo Trewhela N., Patricio Donoso P., Miguel Angel Cumsille   +4 more
doaj  

Comparative effectiveness and safety of adjuvant trastuzumab plus pertuzumab versus trastuzumab emtansine in HER2-positive breast cancer with residual disease after neoadjuvant therapy: a real-world retrospective study

Frontiers in Oncology
PurposeTo compare the effectiveness, safety, and tolerability of adjuvant trastuzumab plus pertuzumab (HP) versus trastuzumab emtansine (T-DM1) in patients with HER2-positive breast cancer with residual invasive disease after neoadjuvant therapy, and to ...
Zhenghua Liu, Zhenghua Liu, Xinyu Wang, Xinyu Wang, Jiayan Gai, Jiayan Gai, Chen Wang, Chen Wang, Xinlu Yi, Xinlu Yi, Yufei Liu, Yufei Liu, Tao Zhou, Tao Zhou   +13 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Therapy-induced immunoediting and the evolution of cancer immune escape

Frontiers in Immunology
Anticancer therapy can eliminate immune-visible tumour cells while simultaneously imposing selective pressures that favour residual immune-evasive populations.
Shuang Meng, Zibo Wang
doaj   +1 more source

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]

, 2001
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Gameiro, P, Diamond, J, Foroni, L, Silva, AL, Mehta, AB, Prentice, HG, Carrara, P, Vieira, S, Guimaraes, JE, Parreira, A, Hoffbrand, AV, de Sousa, AB   +11 more
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Therapy‐Induced ECM Remodeling Creates a Transient Immune Barrier in Residual Melanoma

Advanced Science
Targeted therapies reshape the tumor not only by eliminating malignant cells but also by altering the stromal and immunologic adaptations that emerge during treatment, which remain incompletely defined.
Chia‐Hsin Hsu, Jingyi Chen, Keng‐Jung Lee, Leanne R. Donahue, Danielle Kacaj, Sean P. McDonough, Andrew C. White   +6 more
doaj   +1 more source

The association between residual disease and the risk of future disease flares in axial spondyloarthritis: A longitudinal study

Objectives: To assess, in patients with axial spondyloarthritis (axSpA), whether the presence of clinically relevant signs or symptoms (‘residual disease’) while in an inactive disease or low disease activity (ID/LDA) state increases the risk of future ...
Renet, Ellen, Webers, Casper, Vonkeman, Harald E., Smits, Marius L.; id_orcid, van Tubergen, Astrid   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Minimal residual disease [PDF]

Bone Marrow Transplantation, 2001
T. Szczepański, J.J.M. van Dongen
  +5 more sources