Results 81 to 90 of about 1,955,453 (343)

The Residue Chemistry Transformation Linked to the Fungi Keystone Taxa during Different Residue Tissues Incorporation into Mollisols in Northeast China

open access: yesAgriculture
Managing carbon input from crop straw in cropland ecosystems could increase soil organic carbon (SOC) sequestration to achieve C neutrality and mitigate climate change.
Qilin Zhang   +6 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE

open access: yesNature Communications
The multidrug efflux transporter EmrE from Escherichia coli requires anionic residues in the substrate binding pocket for coupling drug transport with the proton motive force. Here, we show how protonation of a single membrane embedded glutamate residue (
Jianping Li   +9 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Essential Trace Elements in Three Species of Dolphins Stranded in the Croatian Part of the Adriatic Sea from 1995 to 2013

open access: yesAnimals
Trace elements are widely distributed in the environment and are considered essential when their deficiency leads to impaired biological function. This study aimed to quantify concentrations of two essential trace elements—copper (Cu) and zinc (Zn)—in ...
Maja Đokić   +6 more
doaj   +1 more source

Developing an Acidic Residue Reactive and Sulfoxide-Containing MS-Cleavable Homobifunctional Cross-Linker for Probing Protein–Protein Interactions

open access: yesAnalytical Chemistry, 2016
Cross-linking mass spectrometry (XL-MS) has become a powerful strategy for defining protein–protein interactions and elucidating architectures of large protein complexes.
Craig B. Gutierrez   +5 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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