Results 41 to 50 of about 1,946,548 (348)

Analysis of the stability and affinity of BlaR-CTD protein to β-lactam antibiotics based on docking and mutagenesis studies

Journal of Biological Engineering, 2019
Owing to the thermal instability and low affinity of BlaR-CTD to some β-lactams, the receptor assay based on BlaR-CTD is limited in the detection of abundant variety of drugs and the result is often unstable.
Jianan Ning, Saeed Ahmed, Guyue Cheng, Ting Chen, Yulian Wang, Dapeng Peng, Zonghui Yuan   +6 more
doaj   +1 more source

Determination of Susceptibility Breakpoint for Cefquinome against Streptococcus suis in Pigs

Antibiotics, 2021
Streptococcus suis (S. suis), a zoonotic pathogen, causes severe diseases in both pigs and human beings. Cefquinome can display excellent antibacterial activity against gram-negative and gram-positive bacteria.
Kun Mi, Mei Li, Lei Sun, Yixuan Hou, Kaixiang Zhou, Haihong Hao, Yuanhu Pan, Zhenli Liu, Changqing Xie, Lingli Huang   +9 more
doaj   +1 more source

Binomial residues

Annales de l'Institut Fourier, 2002
A binomial residue is a rational function defined by a hypergeometric integral whose kernel is singular along binomial divisors. Binomial residues provide an integral representation for rational solutions of A-hypergeometric systems of Lawrence type. The space of binomial residues of a given degree, modulo those which are polynomial in some variable ...
Cattani, E, Dickenstein, A, Sturmfels, B
openaire   +2 more sources

Preparation of Aditoprim Injection against Streptococcus suis in Pigs and a Dose Regimen Based on Pharmacokinetic-Pharmacodynamic Modeling

Pharmaceutics, 2022
In order to effectively treat the infection of Streptococcus suis and reduce the emergence of drug-resistant bacteria, an aditoprim (ADP) injection was developed in this study.
Wei Qu, Mengxiao Dong, Yuanhu Pan, Shuyu Xie, Zonghui Yuan, Lingli Huang   +5 more
doaj   +1 more source

Preparation, characterization and pharmacokinetics of cyadox nanosuspension

Scientific Reports, 2017
An increase in number of newly developed synthetic drugs displays bioavailability constraints because of poor water solubility. Nanosuspensions formulation may help to overwhelm these problems by increasing dissolution velocity and saturation solubility.
Adeel Sattar, Dongmei Chen, Lishun Jiang, Yuanhu Pan, Yanfei Tao, Lingli Huang, Zhenli Liu, Shuyu Xie, Zonghui Yuan   +8 more
doaj   +1 more source

Residual Networks of Residual Networks: Multilevel Residual Networks [PDF]

IEEE Transactions on Circuits and Systems for Video Technology, 2018
IEEE Transactions on Circuits and Systems for Video Technology ...
Ke Zhang, Miao Sun, Tony X. Han, Xingfang Yuan, Liru Guo, Tao Liu   +5 more
openaire   +2 more sources

ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins

Nucleic Acids Res., 2006
ScanProsite——is a new and improved version of the web-based tool for detecting PROSITE signature matches in protein sequences. For a number of PROSITE profiles, the tool now makes use of ProRules—context-dependent annotation templates—to detect ...
E. D. Castro, Christian J. A. Sigrist, Alexandre Gattiker, Virginie Bulliard, Petra S. Langendijk-Genevaux, E. Gasteiger, A. Bairoch, N. Hulo   +7 more
semanticscholar   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Application of Semi-Mechanistic Pharmacokinetic and Pharmacodynamic Model in Antimicrobial Resistance

Pharmaceutics, 2022
Antimicrobial resistance is a major public health issue. The pharmacokinetic/pharmacodynamic (PK/PD) model is an essential tool to optimize dosage regimens and alleviate the emergence of resistance.
Kun Mi, Kaixiang Zhou, Lei Sun, Yixuan Hou, Wenjin Ma, Xiangyue Xu, Meixia Huo, Zhenli Liu, Lingli Huang   +8 more
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source