Results 21 to 30 of about 249,549 (148)

The link between rheumatic disorders and inborn errors of immunity

EBioMedicine, 2023
Summary: Inborn errors of immunity (IEIs) are immunological disorders characterized by variable susceptibility to infections, immune dysregulation and/or malignancies, as a consequence of damaging germline variants in single genes.
Georgios Sogkas, Torsten Witte
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Postmemory as a form of civic courage. Watchword: resist, resist, resist

Comunicação e Sociedade, 2016
This paper aims to claim the duty of postmemory, in order to think better about the loneliness of memory and to explicit the value of the documentary, as the space and time for a reflection able to welcome and embody those absences that the studies on ...
Sheila Khan
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Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out

Nanomaterials, 2021
The UV-nanoimprint lithography(UV-NIL) fabrication of a novel network of micron-sized channels, forming an open channel microfluidic system is described. Details about the complete manufacturing process, from mastering to fabrication in small batches and
Mirko Lohse, Manuel W. Thesen, Anja Haase, Martin Smolka, Nerea Briz Iceta, Ana Ayerdi Izquierdo, Isbaal Ramos, Clarisa Salado, Arne Schleunitz   +8 more
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Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1

Frontiers in Immunology, 2021
NF-κB1 deficiency is suggested to be the most common cause of common variable immunodeficiency (CVID). NFKB1 encodes for the p105 precursor protein of NF-κB1, which is converted into the active transcriptional subunit p50 through proteasomal processing ...
Manfred Anim, Manfred Anim, Georgios Sogkas, Georgios Sogkas, Gunnar Schmidt, Natalia Dubrowinskaja, Torsten Witte, Reinhold Ernst Schmidt, Reinhold Ernst Schmidt, Faranaz Atschekzei, Faranaz Atschekzei   +10 more
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Common Variable Immunodeficiency-Associated Cancers: The Role of Clinical Phenotypes, Immunological and Genetic Factors

Frontiers in Immunology, 2022
ObjectiveThe aim of this study was to investigate the prevalence of cancer and associating clinical, immunological, and genetic factors in a German cohort of patients with common variable immunodeficiency (CVID).MethodsIn this retrospective monocenter ...
Luzia Bruns, Victoria Panagiota, Sandra von Hardenberg, Gunnar Schmidt, Ignatius Ryan Adriawan, Eleni Sogka, Stefanie Hirsch, Gerrit Ahrenstorf, Torsten Witte, Torsten Witte, Reinhold Ernst Schmidt, Reinhold Ernst Schmidt, Faranaz Atschekzei, Faranaz Atschekzei, Georgios Sogkas, Georgios Sogkas   +15 more
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Resistance to “Castration-Resistant” [PDF]

The Oncologist, 2014
The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
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Resistance-resistant antibacterial treatment strategies

Frontiers in Antibiotics, 2023
Antibiotic resistance is a major danger to public health that threatens to claim the lives of millions of people per year within the next few decades. Years of necessary administration and excessive application of antibiotics have selected for strains that are resistant to many of our currently available treatments. Due to the high costs and difficulty
Batchelder, Jonathan I., Hare, Patricia J., Mok, Wendy W. K.   +2 more
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Comparison of Three Expanded-Spectrum Cephalosporin Hydrolysis Assays and the NG-Test CTX-M Multi Assay That Detects All CTX-M-Like Enzymes

Diagnostics, 2022
Rapid detection of expanded-spectrum cephalosporins (ESC) hydrolysing enzymes is crucial to implement infection control measures and antibiotic stewardship.
Camille Gonzalez, Christian Moguet, Arnaud Chalin, Saoussen Oueslati, Laurent Dortet, Stéphanie Simon, Hervé Volland, Thierry Naas   +7 more
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Resisting Bacterial Drug Resistance [PDF]

Chemistry & Biology, 2003
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
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Undetectable Production of the VIM-1 Carbapenemase in an Atlantibacter hermannii Clinical Isolate

Frontiers in Microbiology, 2021
The differential expression of VIM-1 in Atlantibacter hermannii WEB-2 and Enterobacter hormaechei ssp. hoffmannii WEB-1 clinical isolates from a rectal swab of a hospitalized patient in France was investigated. A.
Delphine Girlich, Rémy A. Bonnin, Rémy A. Bonnin, Alexis Proust, Thierry Naas, Thierry Naas, Thierry Naas, Laurent Dortet, Laurent Dortet, Laurent Dortet   +9 more
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