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By definition, the terms sepsis and septic shock refer to a potentially fatal infectious state in which the early administration of an effective antibiotic is the most significant determinant of the outcome. Because of the global spread of resistant bacteria, the efficacy of antibiotics has been severely compromised. S.
Yasemin, Cag +4 more
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Chemotherapy Resistance Mechanisms [PDF]
Resistance to chemotherapy is a major problem in oncology. The drug resistance in breast cancer shares most traits with other solid tumours. As a result of studies of cell lines and animal tumours a number of drug resistance factors have been identified but only limited data from human tumours are available.
U, Ringborg, A, Platz
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Mechanisms of drug resistance: daptomycin resistance [PDF]
Daptomycin (DAP) is a cyclic lipopeptide with in vitro activity against a variety of Gram‐positive pathogens, including multidrug‐resistant organisms. Since its introduction into clinical practice in 2003, DAP has become an important key frontline antibiotic for severe or deep‐seated infections caused by Gram‐positive organisms.
Truc T, Tran +2 more
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Mechanisms of drug resistance: quinolone resistance [PDF]
Quinolone antimicrobials are synthetic and widely used in clinical medicine. Resistance emerged with clinical use and became common in some bacterial pathogens. Mechanisms of resistance include two categories of mutation and acquisition of resistance‐conferring genes.
David C, Hooper, George A, Jacoby
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Mechanisms of Antibiotic Resistance [PDF]
ABSTRACT Emergence of resistance among the most important bacterial pathogens is recognized as a major public health threat affecting humans worldwide. Multidrug-resistant organisms have not only emerged in the hospital environment but are now often identified in community settings, suggesting that reservoirs of antibiotic-resistant bacteria ...
Jose M, Munita, Cesar A, Arias
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Imipenem Resistance Mediated by blaOXA-913 Gene in Pseudomonas aeruginosa
Treatment of infectious diseases caused by carbapenem-resistant Pseudomonas aeruginosa is becoming a greater challenge. This study aimed to identify the imipenem resistance mechanism in P. aeruginosa isolated from a dog. Minimum Inhibitory Concentration (
Dong-Chan Moon +7 more
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Italian ryegrass (Lolium multiflorum; LOLMU) is one of the most troublesome weeds in temperate regions in the world. This weed species interfere with wheat, corn, rye, and oat, causing significant crop yield losses.
Joanei Cechin +7 more
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Background: Acinetobacter baumannii’s (A. baumannii) growing resistance to all available antibiotics is of concern. The study describes a colistin-resistant A. baumannii isolated at a clinical facility from a tracheal aspirate sample.
Noel-David Nogbou +5 more
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Elymus nutans is a perennial grass of the Gramineae family. Due to its cold-resistance and nutrition deficiency tolerance, it has been applied to the ecological restoration of degraded alpine grassland on the Qinghai-Tibet Plateau.
Haijuan Zhang +11 more
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Mechanisms of antibiotic resistance [PDF]
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major ...
Lin, Jun +5 more
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