Results 11 to 20 of about 1,444,587 (217)

Transcriptome Analysis Identifies Candidate Target Genes Involved in Glyphosate-Resistance Mechanism in Lolium multiflorum

Plants, 2020
Italian ryegrass (Lolium multiflorum; LOLMU) is one of the most troublesome weeds in temperate regions in the world. This weed species interfere with wheat, corn, rye, and oat, causing significant crop yield losses.
Joanei Cechin, Cristiano Piasecki, Daiane P. Benemann, Frederico S. Kremer, Vanessa Galli, Luciano C. Maia, Dirceu Agostinetto, Leandro Vargas   +7 more
doaj   +1 more source

Whole-Genome Sequencing of a Colistin-Resistant Acinetobacter baumannii Strain Isolated at a Tertiary Health Facility in Pretoria, South Africa

Antibiotics, 2022
Background: Acinetobacter baumannii’s (A. baumannii) growing resistance to all available antibiotics is of concern. The study describes a colistin-resistant A. baumannii isolated at a clinical facility from a tracheal aspirate sample.
Noel-David Nogbou, Mbudzeni Ramashia, Granny Marumo Nkawane, Mushal Allam, Chikwelu Lawrence Obi, Andrew Munyalo Musyoki   +5 more
doaj   +1 more source

Non-targeted metabolomics analysis reveals the mechanism of arbuscular mycorrhizal symbiosis regulating the cold-resistance of Elymus nutans

Frontiers in Microbiology, 2023
Elymus nutans is a perennial grass of the Gramineae family. Due to its cold-resistance and nutrition deficiency tolerance, it has been applied to the ecological restoration of degraded alpine grassland on the Qinghai-Tibet Plateau.
Haijuan Zhang, Hexing Qi, Guangxin Lu, Xueli Zhou, Xueli Zhou, Junbang Wang, Jingjing Li, Kaifu Zheng, Yuejun Fan, Huakun Zhou, Jiuluan Wang, Chu Wu   +11 more
doaj   +1 more source

Diffraction anisotropy falloff in the direction of the detergent belt for two centered monoclinic crystals of OmpF

Data in Brief, 2016
This data article describes the anisotropy of diffraction observed for the centered monoclinic crystals of OmpF reported in “Two different centered monoclinic crystals of the E.
Vincent Chaptal, Arnaud Kilburg, David Flot, Benjamin Wiseman, Nushin Aghajari, Jean-Michel Jault, Pierre Falson   +6 more
doaj   +1 more source

PARP Inhibitors in Ovarian Cancer: The Route to “Ithaca”

Diagnostics, 2019
Poly (ADP-ribose) polymerase (PARP) inhibitors are a novel class of therapeutic agents that target tumors with deficiencies in the homologous recombination DNA repair pathway.
Stergios Boussios, Afroditi Karathanasi, Deirdre Cooke, Cherie Neille, Agne Sadauskaite, Michele Moschetta, Nikolaos Zakynthinakis-Kyriakou, Nicholas Pavlidis   +7 more
doaj   +1 more source

The role of B2M in cancer immunotherapy resistance: function, resistance mechanism, and reversal strategies [PDF]

Frontiers in Immunology
Han X, Zhang J, Li W, Huang X, Wang X, Wang B, Gao L, Chen H.   +7 more
exaly   +2 more sources

The Resistance Mechanisms of Anilinopyrimidine Fungicide Pyrimethanil in Sclerotinia sclerotiorum

Journal of Fungi
The necrotrophic pathogen Sclerotinia sclerotiorum is widely distributed and infects a broad range of hosts, making it one of the most economically damaging plant pathogens.
Yanfen Wang, Zeyuan Chen, Tiancheng Liu, Xupeng Gao, Yanchao Shi, Honghui Wu, Runqiang Liu, Yunchao Kan, Hao Yu, Feng Zhou   +9 more
doaj   +1 more source

Study on the mechanism of KRAS R68G secondary mutation-induced resistance to KRASG12D-targeted inhibitor MRTX1133

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To explore the mechanism at the atomic level by which the KRASG12D/R68G mutation induces tumor cell resistance to MRTX1133.Methods·The crystal structure data of the KRASG12D-MRTX1133 complex were obtained from the RCSB Protein Data Bank (PDB ...
WANG Gaoming, CUI Ran, LI Yanjing, LIU Yingbin   +3 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Iterative Upgrading of Small Molecular Tyrosine Kinase Inhibitors for EGFR Mutation in NSCLC: Necessity and Perspective

Pharmaceutics, 2021
Molecular targeted therapy has been reported to have fewer adverse effects, and offer a more convenient route of administration, compared with conventional chemotherapy. With the development of sequencing technology, and research on the molecular biology
Jing Zhu, Qian Yang, Weiguo Xu
doaj   +1 more source