Results 61 to 70 of about 3,772,305 (302)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

The Role of Employees in a Process of Change – A Case Study for the Romanian Organizations [PDF]

open access: yesRevista de Management Comparat International, 2013
Change is inevitable and in order to successfully manage a process of change, business leaders have to acknowledge and understand the forces that drive it.
Marian NĂSTASE   +2 more
doaj  

Ready for Changes? The Influence of General Self-Efficacy and Resistance to Change on Managers' Future Competence Requirements

open access: yesEuropean Journal of Business Science and Technology, 2018
With this study, we will test the interrelations between the psychological concept of self-efficacy of managers and its influences on the resistance to change.
Jürgen Mühlbacher, Tom Siebenaler
doaj   +1 more source

Design and fabrication of a micro Coulter counter with thin film electrodes [PDF]

open access: yes, 2006
We report a new approach for micro Coulter counter with thin film electrodes. Traditional Coulter counter measures DC resistance change to sense particles passing through an aperture between two flow chambers.
Tai, Yu-Chong, Zheng, Siyang
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The importance of internal communication in organizational change: Case study of the structural change in a Belgian government agency [PDF]

open access: yes, 2016
Internal communication is an essential element to create willingness to change in organizations (Elving 2005a, 2005b; Clampitt et al. 2000; Armenakis et al. 2007).
Van Leuven, Sarah, Van Praet, Ellen
core   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

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