Results 81 to 90 of about 1,503,887 (312)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Identification of a Major Locus for Lodging Resistance to Typhoons Using QTL Analysis in Rice
We detected a new target quantitative trait locus (QTL) for lodging resistance in rice by analyzing lodging resistance to typhoons (Maysak and Haishen) using a scale from 0 (no prostrating) to 1 (little prostrating or prostrating) to record the ...
Eun-Gyeong Kim +11 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sanctioning resistance to sexual objectification: An integrative system justification perspective [PDF]
In this article, we describe an integrated theoretical approach for promoting resistance to the system of sexual objectification. Drawing from system justification and objectification theories, we propose a two-arm approach that would harness the system ...
Tylka, Tracy L., Calogero, Rachel M.
core +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The Impact of Job Stress on Flourishing Through the Mediation of Resistance to Change and the Moderation of Extroversion among Teachers [PDF]
Purpose: Employee flourishing, especially among teachers, is one of the main components of mental health and professional well being in educational environments, and it is recognized as a key indicator for evaluating the positive functioning and ...
Farshid Aslani +3 more
doaj +1 more source
How not to do Change Management: The birth of a Murdoch University School
Universities in Australia, as pan of the public sector and reliant on public funding, are increasingly the subject of pressure for greater accountability and organisational change.
Holloway, D.A., van Rhyn, D.
core
Late blight (Phytophthora infestans) can have devastating effects on tomato production over the whole world. Most of the commercial cultivars of tomato, Solanum lycopersicum, are susceptible.
Visser, R.G.F. +5 more
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source

