Results 81 to 90 of about 3,772,305 (302)

Progressive amorphization of GeSbTe phase-change material under electron beam irradiation

, 2019
Fast and reversible phase transitions in chalcogenide phase-change materials (PCMs), in particular, Ge-Sb-Te compounds, are not only of fundamental interests, but also make PCMs based random access memory (PRAM) a leading candidate for non-volatile ...
Jia, Chun-Lin, Jiang, Ting-Ting, Lu, Lu, Ma, Chuan-Sheng, Rao, Feng, Wang, Jiang-Jing, Zhang, Dan-Li, Zhang, Wei   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

L'ascenseur et l'escalier — la lutte contre le SIDA au Cameroun

SAHARA-J, 2004
HIV/AIDS infection has spread like wildfire in the countries of sub-saharan Africa. In order to fight that pandemic, Cameroon has organised itself by setting up, with the assistance of bilateral and multilateral partners, a national structure with the ...
Jacques-Philippe Tsala Tsala
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Resistance to Change in the Romanian Educational System: Challenges and Opportunities [PDF]

Revista de Știinţe Educaţiei
The traditional perspective on education, teaching, and learning is no longer sufficient in fluid societies exposed to dramatic and rapid changes. The need for continuous educational reform is evident.
Ioana DARJAN
doaj   +1 more source

Resistance to Position Change, Motivated Reasoning, and Polarization [PDF]

People seem more divided than ever before over social and political issues, entrenched in their existing beliefs and unwilling to change them. Empirical research on mechanisms driving this resistance to belief change has focused on a limited set of well ...
De Brigard, Felipe, Henne, Paul, Stanley, Matthew L., Yang, Brenda   +3 more
core  

A Theory of Judicial Constitutional Design [PDF]

, 2017
The purpose of this paper is to describe how judges engage in constitutional design, irrespective of legal tradition. I examine in great detail the role of the judge: as a conflict solver, as a member of an institution, as part of the political system ...
Mancilla, Roberto
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Building the normative dimension(s) of a global polity [PDF]

, 2003
Globalisation is not what it used to be. Earlier debates over how to read the indicators of economic liberalisation and the impact of technological expansion have now been joined by the increasingly pressing need to explore the social, environmental and ...
Brassett, James, Higgott, Richard A.
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source