Results 31 to 40 of about 86,878,094 (191)
Not all elevated hormones are toxic: A case of thyroid hormone resistance
Journal of Family Medicine and Primary Care, 2016 Resistance to thyroid hormone syndrome (RTH) is a rare disorder and is usually inherited as dominantly negative autosomal trait. RTH is caused by mutations in the thyroid hormone receptor beta.
Rajeev Philip +3 more
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Thyroid Hormone Resistance Syndromes
, 2019 Syndromes with impaired sensitivity to thyroid hormone (TH) include three types of resistance to thyroid hormone (RTH) syndromes (RTHβ, RTHα, and nonTR-RTH) and also include patients with defects in TH transport into cells (thyroid hormone cell membrane ...
Refetoff, Samuel +3 more
core +1 more source
The zebrafish model to identify new genes involved in thyroid development [PDF]
, 2010 Thyroid organogenesis is a very complex developmental process that leads to the formation of an organ able to produce specific hormones through specification, migration, structural organization and functional differentiation of thyroid precursor cells ...
Porreca, Immacolata
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Clinical Diabetes and Endocrinology, 2017 There are two genes that express the major thyroid hormone receptor isoforms. Mutations in both these genes have given rise to Resistance to Thyroid Hormone (RTH) syndromes (RTHβ, RTHα) that can have variable phenotypes for mutations of the same receptor
Brijesh K. Singh, Paul M. Yen
doaj +1 more source
Journal of Medical Case Reports, 2012 Introduction Resistance to thyroid hormone is a syndrome caused by thyroid hormone receptor β mutations, which are usually inherited in an autosomal-dominant pattern.
Yatsuga Shuichi +6 more
doaj +1 more source
Identification of a novel THRB mutation causing thyroid hormone resistance syndrome [PDF]
Archives of Endocrinology and MetabolismResistance to thyroid hormone syndrome (RTHS) is a rare disorder caused by mutations in the thyroid hormone receptor beta (THRB) gene, resulting in impaired action of thyroid hormones on target tissues and organs.
Jing Yang +3 more
doaj +2 more sources
Alopecia: Association with Resistance to Thyroid Hormones
Journal of Pediatric Endocrinology and Metabolism, 2009 Resistance to thyroid hormone (RTH) syndrome is caused by thyroid hormone beta receptor (TRbeta) mutations. Goiter, learning disabilities, psychological abnormalities, sinus tachycardia, hearing deficits, short stature, and growth delay are among the most common symptoms in patients with RTH.
Güran, Tülay +3 more
openaire +5 more sources
The interpretation and management of thyroid disorders
South African Family Practice, 2013 This short review is intended to simplify the interpretation of thyroid function tests (TFTs) in general practice. The relationship between thyroid hormones and the use of TFTs, as well as thyroid antibodies, is discussed.
M. Dednam
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BMC Endocrine Disorders, 2023 Background The association between thyroid hormone sensitivity and thyroid cancer is unknown, and we aimed to investigate the association between sensitivity to thyroid hormone indices and papillary thyroid carcinoma (PTC) in Chinese patients with ...
Jie Sun +4 more
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Syndrome of Resistance to Thyroid Hormone: Insights into Thyroid Hormone Action
Experimental Biology and Medicine, 1996 Thyroid hormones (T3, T4) exert multiple cellular effects through nuclear thyroid hormone receptors (TR alpha, TR beta). Thyroid hormone receptors are transcription factors that act by altering patterns of gene expression. Resistance to thyroid hormone (RTH) is a rare disorder caused by mutations in the TR beta gene.
P, Kopp, K, Kitajima, J L, Jameson
openaire +2 more sources