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Resistance to Thyroid Hormone

Hormone Research, 2009
Resistance to thyroid hormone (RTH) is usually dominantly inherited and is characterized by elevated free thyroid hormones in the serum and failure to suppress pituitary thyroid stimulating hormone (TSH) secretion with variable refractoriness to hormone action in peripheral tissues.
Christian G. Bien   +79 more
openaire   +3 more sources

Thyroid hormone resistance

Postgraduate Medical Journal, 2008
Abstract Thyroid hormone resistance (THR) is a rare syndrome of reduced end organ sensitivity. Patients with THR have elevated serum free thyroxine (FT4), free triiodothyronine (FT3), but normal or slightly elevated serum thyrotropin values.
N K, Agrawal   +4 more
openaire   +3 more sources

Thyroid Hormone Resistance

Annual Review of Medicine, 1992
Generalized resistance to thyroid hormone (GRTH) encompasses a heterogeneous group of conditions characterized by reduced responses of target tissues to thyroid hormone due to defects at the site of hormone action. In the majority of patients, GRTH is inherited as a dominant trait associated with mutations in the hormone-binding domain of the thyroid ...
R E, Weiss, S, Refetoff
openaire   +3 more sources

Thyroid hormone resistance

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2006
Resistance to thyroid hormone (RTH) is a rare autosomal dominant inherited syndrome of reduced end-organ responsiveness to thyroid hormone. Patients with RTH have elevated serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations and normal or slightly elevated serum thyroid stimulating hormone (TSH) level.
Tolulope O, Olateju   +1 more
openaire   +2 more sources

Resistance to Thyroid Hormone

Reviews in Endocrine and Metabolic Disorders, 2000
The syndromes of resistance to thyroid hormone (RTH) are generally characterized by reduced tissue responsiveness to thyroid hormone (TH) despite elevated circulating levels of free T 3 and/or T 4 (Refetoff et al., 1993). It is associated with an inappropriately normal or raised serum TSH characteristic of impaired thyrotroph sensitivity.
R E, Weiss, S, Refetoff
openaire   +2 more sources

Resistance to Thyroid Hormone in Pregnancy

Obstetrics & Gynecology, 2008
Resistance to thyroid hormone manifests as high serum levels of free thyroxine and free triiodothyronine, with nonsuppressed thyroid stimulating hormone (TSH) levels. We report a case series of three patients with this condition, the changes in thyroid function tests during their pregnancies, and their obstetric outcome.Three pregnant women with ...
Simi, Dhingra   +3 more
openaire   +2 more sources

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