Results 181 to 190 of about 3,703,855 (310)

Promoter hypomethylation drives ABCB1-mediated carfilzomib resistance in multiple myeloma. [PDF]

Clin Epigenetics
Han S, Haertle L, Munawar U, Truger M, Hainold AS, Lee CY, Kurian S, Verbruggen C, Nerreter S, Vogt C, Besant E, Rein N, Lehmann J, Köppel M, Tamamushi Y, Zhou X, Steinbrunn T, Haaf T, Küster B, Slaby O, Haferlach C, Einsele H, Rasche L, Waldschmidt J, Besse A, Driessen C, Besse L, Kortüm KM.   +27 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Genome-wide association studies builds a predictive model and reveals novel resistance features for macrolide-resistant Bordetella pertussis. [PDF]

J Antimicrob Chemother
Chen J, Liang G.
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Inhibition of CDK9 sensitizes multidrug resistant ovarian cancer cells to paclitaxel. [PDF]

Sci Rep
Wang J, Hornicek FJ, Shi H, Feng W, Duan Z.   +4 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Carriage of Antibiotic-Resistant <i>E</i>. <i>Coli</i> by Mixed Dog Breeds in Kasarani Subcounty, Kenya: A Public Health Concern. [PDF]

Vet Med Int
Bosibori OE, Bebora LC, Mbugua S.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Proteomic Insights into Effects of a Camel Milk-Derived Peptide on Insulin Resistance: Modulation of Metabolic, Oxidative, and Signaling Pathways. [PDF]

Foods
Mohamed IK, Hua Y, Kong X, Li X, Chen Y, Zhang C, Fall M, Hassan Ramadhan A.   +7 more
europepmc   +1 more source

Resisting readers and resistant texts [PDF]

Journal of Advanced Nursing, 2008
openaire   +2 more sources