Results 161 to 170 of about 2,503,389 (311)

WHO Bacterial Priority Pathogens List: a 32-year global trend and inequality analysis of antimicrobial resistance burden by age and region. [PDF]

BMJ Public Health
Yin Z, Tan J, Liu X, Xie Y, Chen Y, Zhang Y.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Disseminated Trimethoprim/Sulfamethoxazole-Resistant Nocardiosis in Renal Transplant Recipient, India. [PDF]

Emerg Infect Dis
Kordcal SR, Maula MT, Suguna VM, Khan AR, Ranjan R, Spalkit S, Nambirajan A, Singh G, Nischal N, Xess I, Soneja M.   +10 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Nickel Alloy, Corrosion- and Heat-Resistant, Seamless Tubing, 47.5Ni - 22Cr - 1.5Co - 9.0Mo - 0.60W - 18.5Fe (HASTELLOY® X), Solution Heat Treated

<div class="section abstract"> <div class="htmlview paragraph">This specification covers a corrosion- and heat-resistant nickel alloy in the form of seamless tubing.</div></div>
null null, AMS F Corrosion and Heat Resistant Alloys Committee   +1 more
core   +1 more source

Targeting the TBK1-p62 condensate axis restores sensitivity to EGFR-TKIs in resistant lung cancer. [PDF]

Protein Cell
Song Y, Shao C, Zhang Y, Yang M, Liu Y, Chen S, Gao J, Li Z, Li B, Yao X, Liu X, Ruan K, Du Y.   +12 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Steel, Corrosion-Resistant, Sheet, Strip, and Plate, 15Cr - 6.5Ni - 0.75Mo - 0.60Cb - 1.5Cu (Custom 450®), Solution Heat Treated, Precipitation Hardenable

<div class="section abstract"> <div class="htmlview paragraph">This specification covers a corrosion-resistant steel in the form of sheet, strip, and plate.</div></div>
null null, AMS F Corrosion and Heat Resistant Alloys Committee   +1 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Efficient phenotyping of banana (Musa spp.) germplasm for resistance to five biotic constraints using Partially replicated (P-rep) design. [PDF]

PLoS One
Kanaabi R, Mwanje G, Serebe C, Mpanda H, Jomanga K, Uwimana B, Vuylsteke M, Brown A, Swennen R, Nakato GV.   +9 more
europepmc   +1 more source