Results 51 to 60 of about 3,559,343 (361)

Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

Nature Reviews Microbiology, 2020
Antibiotic-resistant bacterial infections arising from acquired resistance and/or through biofilm formation necessitate the development of innovative ‘outside of the box’ therapeutics.
J. M. Makabenta, Ahmed Nabawy, Cheng-Hsuan Li, Suzannah M. Schmidt-Malan, Robin Patel, V. Rotello   +5 more
semanticscholar   +1 more source

The oxidation mechanisms of Pt and reactive elements modified AlCoCrFeNi2.1 eutectic high-entropy alloy at high temperature

Journal of Materials Research and Technology
AlCoCrFeNi2.1 eutectic high-entropy alloys (EHEAs) show great potential in high-temperature applications due to the dual-phase lamellar structure. In this work, the high-temperature oxidation behavior and scaling mechanisms of three AlCoCrFeNi2.1 EHEAs ...
Qinying Huang, Yuzhuo Li, Peng Zhang, Yingfei Yang, Shengfeng Zhou, Pan Ren, Qiwei Wang, Wei Li, Fuhui Wang   +8 more
doaj   +1 more source

Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology

Clinical Microbiology Reviews, 2018
Staphylococcus aureus, a major human pathogen, has a collection of virulence factors and the ability to acquire resistance to most antibiotics. This ability is further augmented by constant emergence of new clones, making S. aureus a “superbug.” Clinical
Sahreena S. Lakhundi, Kunyan Zhang
semanticscholar   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Combining organophosphate treated wall linings and long-lasting insecticidal nets for improved control of pyrethroid resistant Anopheles gambiae. [PDF]

, 2014
BACKGROUND: New approaches to delivering insecticides need to be developed to improve malaria vector control. Insecticidal durable wall lining (DL) and net wall hangings (NWH) are novel alternatives to indoor residual spraying which can be produced in a ...
Mark Rowland, Dabire Roch, Tchicaya, Emile, Johnson, Paul, Roch Dabire, Rowland Mark, Ranson, Hilary, N'Fale, S., Dabire, R., Ngufor, C., Koudou, B., Koudou, Benjamin, Rowland, Mark, Johnson, P., Ranson, H., Ngufor Corine, Tchicaya, E., Ranson, Hilary; id_orcid, Benjamin Koudou, Sagnon N'Fale, Paul Johnson, Mark Rowl, Koudou Benjamin, Dabire, Roch, N'Fale, Sagnon, Tchicaya Emile, Rowland, M., Ngufor, Corine, Emile Tchicaya, N'Fale Sagnon, Johnson Paul, Corine Ngufor, Hilary Ranson, Ranson Hilary   +33 more
core   +1 more source

Cinnamaldehyde supplementation in sows and their offspring: effects on colostrum and milk composition, performance, redox status and intestinal health

Journal of Animal Science and Biotechnology
Background Maternal nutrition significantly influences offspring development. This study investigated the effects of maternal or post-weaning cinnamaldehyde (CA) supplementation in sows and their offspring on reproductive performance and health.
Junqi Jin, Shiya Liu, Qiang Zhou, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, Hefeng Luo, Xiuming Liu, De Wu, Lianqiang Che   +11 more
doaj   +1 more source

Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

Clinical Infectious Diseases, 2017
Background. Candida auris, a multidrug-resistant yeast that causes invasive infections, was first described in 2009 in Japan and has since been reported from several countries. Methods. To understand the global emergence and epidemiology of C.
S. Lockhart, Kizee A. Etienne, S. Vallabhaneni, J. Farooqi, A. Chowdhary, N. Govender, A. Colombo, B. Calvo, Christina A. Cuomo, C. Desjardins, E. Berkow, M. Castanheira, R. Magobo, K. Jabeen, R. Asghar, J. Meis, Brendan R. Jackson, T. Chiller, A. Litvintseva   +18 more
semanticscholar   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Cefotaxime-Resistant Salmonella enterica in Travelers Returning from Thailand to Finland

Emerging Infectious Diseases, 2014
During 1993–2011, cefotaxime resistance among Salmonella enterica isolates from patients in Finland increased substantially. Most of these infections originated in Thailand; many were qnr positive and belonged to S.
Marianne Gunell, Laura Aulu, Jari Jalava, Susanna Lukinmaa-Åberg, Monica Österblad, Jukka Ollgren, Pentti Huovinen, Anja Siitonen, Antti J. Hakanen   +8 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source