Results 71 to 80 of about 3,559,343 (361)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Genome Sequence of a Recently Emerged, Highly Transmissible, Multi-Antibiotic- and Antiseptic-Resistant Variant of Methicillin-Resistant Staphylococcus aureus, Sequence Type 239 (TW)

, 2010
The Sanger Institute is core funded by the Wellcome Trust. Funding for the sequencing of the TW20 genome was provided by Guy’s and St. Thomas’ Charity. J.D.E.
Edgeworth, Jonathan D., Quail, MA, Bentley, SD, Quail, Michael A., Parkhill, Julian, Corton, C, Parkhill, J, Lindsay, JA, Lindsay, Jodi A., Edgeworth, JD, Pathak, Smriti, Batra, R, Pathak, S, Bentley, Stephen D., Holden, MT, Holden, Matthew T. G., Cockfield, Joshua D., Batra, Rahul, Cockfield, JD, Corton, Craig   +19 more
core   +1 more source

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus [PDF]

, 2011
Background: Staphylococcus aureus is a major human pathogen and strains resistant to existing treatments continue to emerge. Development of novel treatments is therefore important.
Barton, Geoffrey J, Peter J Coote, Botting, Catherine H., Katherine A Gould, Geoffrey J Barton, Hinds, Jason, Overton, Ian M., Gould, Katherine A., Coote, Peter J, Gould, Katherine A, Shirran, Sally, Botting, CH, Catherine H Botting, Barton, GJ, Coote, Peter J., Gould, KA, Shirley Graham, Botting, Catherine H, Overton, IM, Ian M Overton, Overton, Ian M, Barton, Geoffrey J., Graham, Shirley, Shirran, S, Overton, Ian M; id_orcid, Hinds, J, Sally Shirran, Coote, PJ, Jason Hinds, Barton, Geoffrey J.; id_orcid, Graham, S   +30 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Resistance in Vancomycin-Resistant Enterococci

Infectious Disease Clinics of North America, 2020
Serious infections owing to vancomycin-resistant enterococci have historically proven to be difficult clinical cases, requiring combination therapy and management of treatment-related toxicity. Despite the introduction of new antibiotics with activity against vancomycin-resistant enterococci to the therapeutic armamentarium, significant challenges ...
William R, Miller, Barbara E, Murray, Louis B, Rice, Cesar A, Arias   +3 more
openaire   +3 more sources

Purification and characterisation of the bacteriocin produced by Lactobacillus plantarum, isolated from Chinese pickle

Czech Journal of Food Sciences, 2014
119 strains of lactic acid bacteria from Chinese pickle were tested for production of antimicrobial compounds (bacteriocins). Among them, strain C8 showed strongly antibacterial activity against Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC ...
Fang Zhou, Hongfei Zhao, Fengling Bai, Piotr Dziugan, Yuen Liu, Bolin Zhang   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Constitutive Activation of the Midgut Response to Bacillus thuringiensis in Bt-Resistant Spodoptera exigua [PDF]

, 2010
Bacillus thuringiensis is the most effective microbial control agent for controlling numerous species from different insect orders. The main threat for the long term use of B. thuringiensis in pest control is the ability of insects to develop resistance.
Ferre, J., Ferré, Juan, CACCIA, SILVIA, Navarro Cerrillo, Gloria, Juan Ferré, Escriche, Baltasar, Navarro-Cerrillo, G., Escriche, B., William J Moar, Silvia Caccia, Herrero, S., de Maagd, Ruud A, de Maagd Ruud A., de Maagd, R.A., Moar William J., Ruud A. de Maagd, Salvador Herrero, S. Herrero, Moar, W.J., W. J. Moar, Hernandez-Martinez, P., Ruud A de Maagd, Moar, William J, Escriche Baltasar, P. Hernández Martínez, Patricia Hernández-Martínez, Navarro-Cerrillo Gloria, Herrero Salvador, Hernández Martínez, Patricia, Gloria Navarro-Cerrillo, Baltasar Escriche, J. Ferré, Hernández-Martínez Patricia, Maagd, R.A., de, William J. Moar, Ferré Juan, Herrero, Salvador, B. Escriche, G. Navarro Cerrillo, R. A. de Maagd, Caccia, S., Caccia Silvia, S. Caccia   +42 more
core   +1 more source

High prevalence of drug-resistant tuberculosis and other mycobacteria among HIV-infected patients in Brazil: a systematic review

Memorias do Instituto Oswaldo Cruz, 2010
There is a little-noticed trend involving human immunodeficiency virus (HIV)-infected patients suspected of having tuberculosis: the triple-treatment regimen recommended in Brazil for years has been potentially ineffective in over 30% of the cases.
Ricardo H Bammann, Liliana A Zamarioli, Valdir S Pinto, Carla MP Vázquez, Marcelo N Litvoc, Giselle B Klautau, Fernando A Fiúza de Melo, Nilton J Cavalcante, Lucilaine Ferrazoli   +8 more
doaj   +1 more source

Divergent clonal evolution of castration resistant neuroendocrine prostate cancer

Nature Medicine, 2016
An increasingly recognized resistance mechanism to androgen receptor (AR)-directed therapy in prostate cancer involves epithelial plasticity, in which tumor cells demonstrate low to absent AR expression and often have neuroendocrine features.
H. Beltran, D. Prandi, J. Mosquera, M. Benelli, L. Puca, J. Cyrta, C. Marotz, Eugenia G. Giannopoulou, B. V. Chakravarthi, S. Varambally, S. Tomlins, D. Nanus, S. Tagawa, E. V. Van Allen, O. Elemento, A. Sboner, L. Garraway, M. Rubin, F. Demichelis   +18 more
semanticscholar   +1 more source