Results 61 to 70 of about 1,598,652 (266)

Performance, Antimicrobial Effect and Carcass Parameters of Finisher Broilers Given Xylopia aethiopica Dried Fruits (Grains of Selim) as Additive

open access: yesAgricultura Tropica et Subtropica, 2014
The effect of graded levels of grains of selim on the performance, gut microbial population and carcass characteristics of finisher broilers was investigated. Two hundred and four (204) 28 days old broiler chicks (Marshal breed) were randomly allotted to
Isikwenu Jonathan Ogagaoghene   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Resisting Bacterial Drug Resistance [PDF]

open access: yesChemistry & Biology, 2003
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire   +2 more sources

Effects of replacing soybean meal with enzymolysis-fermentation compound protein feed on growth performance, apparent digestibility of nutrients, carcass traits, and meat quality in growing-finishing pigs

open access: yesJournal of Animal Science and Biotechnology
Background Addressing the shortage of high-quality protein resources, this study was conducted to investigate the effects of replacing soybean meal (SBM) with different levels of enzymolysis-fermentation compound protein feed (EFCP) in the diets of ...
Yu Cheng   +12 more
doaj   +1 more source

Combined local and systemic bleomycin administration in electrochemotherapy to reduce the number of treatment sessions

open access: yesRadiology and Oncology, 2016
Electrochemotherapy (ECT), a medical treatment widely used in human patients for tumor treatment, increases bleomycin toxicity by 1000 fold in the treated area with an objective response rate of around 80%. Despite its high response rate, there are still
Maglietti Felipe   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Resistance and cross‐resistance to abacavir [PDF]

open access: yesHIV Medicine, 2001
Background Abacavir (ABC) is a potent nucleoside reverse transcriptase inhibitor (NRTI) used in multi‐drug antiretroviral regimens and in combination with other NRTIs, protease and/or non‐nucleoside reverse transcriptase inhibitors (NNRTIs) in both treatment naive and treatment experienced patients.Patterns of resistance Resistance to ABC has been ...
openaire   +2 more sources

Orbital Apex Syndrome Caused by Herpes Zoster in an Immunocompetent Patient: A Case Report

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Orbital apex syndrome (OPS) is determined by ophthalmoplegia, vision loss, and involvement of cranial nerves III, IV, VI, and the first branch of the trigeminal nerve.
Alireza Davoudi   +6 more
doaj  

Rail hidden damage detection based on the modal curvature differences method

open access: yesAdvances in Mechanical Engineering
The rail hidden damage includes rail bottom and rail jaw cracks, which cannot be easily detected during the early development stage, and pose a significant danger and risk of rail-breaking accidents. This paper proposed an effective method to detect rail
Weirong Li   +4 more
doaj   +1 more source

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