Results 121 to 130 of about 32,295 (302)

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

Recent Saccadic Eye Movement Research Uncovers Patterns of Cognitive Dysfunction in Schizophrenia. [PDF]

open access: yes, 2001
The frontal cortex and the subcortical areas of the brain play a major role in the control of thought and action. Eye movements are increasingly used in neuropsychological research to explore the executive and sensorimotor functions of such neural ...
Broerse, Annelies, Crawford, Trevor J.
core  

Treatment-resistant schizophrenia: pathogenesis and treatment strategies.

open access: yes, 2021
Treatment-resistant schizophrenia (TRS) is most defined as an inadequate response in schizophrenia symptoms, despite adequate treatment with two or more antipsychotic medications.
Vasiliauskas, Erikas,   +1 more
core  

An Alien Word? Cosmic Salvation within a Rahnerian Framework

open access: yesThe Heythrop Journal, EarlyView.
Abstract The possibility of life beyond our planet raises serious theological questions for Christians, particularly in the realm of soteriology. How would Jesus of Nazareth relate to such creatures? Is he the ‘universal’ saviour, in the cosmic sense? Or are there other incarnations of the Logos, the Word or Son of God?
Brandon R. Peterson
wiley   +1 more source

Common and unique white matter fractional anisotropy patterns in patients with schizophrenia with medication-resistant auditory verbal hallucinations: a retrospective tract-based spatial statistics study

open access: yesSchizophrenia
Auditory verbal hallucinations (AVHs) are experienced by the majority of patients with schizophrenia and are often resistant to treatment with antipsychotic agents. White matter (WM) tract abnormalities are associated with AVH treatment efficacy. Using a
Chuanjun Zhuo   +8 more
doaj   +1 more source

Psychotic symptoms of sexual nature as core psychopathology in schizophrenia: Case series

open access: yesIndian Journal of Psychiatry
Background: Psychotic symptoms involving sexual content remain underreported in schizophrenia, particularly in Indian settings. Cases: Six patients with schizophrenia presenting with sexually themed delusions or hallucinations as core psychopathology ...
Anjali Sharma   +3 more
doaj   +1 more source

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs   +6 more
wiley   +1 more source

The discursive construction of schizophrenia as a problem of self in relationship

open access: yes, 2011
People with a diagnosis of schizophrenia are thought to experience a „loss‟ of self, theoretically assumed to be the direct result of their "disease‟ or mental illness.
Stanley, Susanne
core  

Darier disease—A review highlighting new insights from the Darier Disease International Task Force

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz   +49 more
wiley   +1 more source

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