Results 131 to 140 of about 32,295 (302)

Clozapine for Treatment-Resistant Schizophrenia

, 2018
This chapter provides a summary of a landmark study on the pharmacologic management of treatment-resistant schizophrenia. This clinical trial, conducted by Kane and colleagues, asks whether clozapine is an effective option in the care of patients with ...
Vinod H. Srihari, Chadrick Lane
core   +1 more source

20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy

Journal of Microscopy, EarlyView.
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford, Colette J. Mustard, Nicole Brace, Antonia L. Pritchard   +3 more
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Sensorimotor gating and clinical outcome following cognitive behaviour therapy for psychosis

, 2012
Background: Prepulse inhibition (PPI) of the startle response refers to the ability of a weak prestimulus to transiently inhibit the response to a closely following strong sensory stimulus.
Peters, Emmanuelle R., Emmanuelle R. Peters, Peters, Emmanuelle R.; id_orcid, Antonova, Elena, Preethi Premkumar, Kuipers, Elizabeth; id_orcid, Satya Raghuvanshi, Aasen, I, Kumari, V, Antonova, E, Ingrid Aasen, Kuipers, Elizabeth, Elizabeth Kuipers, Elena Antonova, Aasen, Ingrid, Premkumar, P, Anilkumar, AP, Kuipers, E, Anilkumar, Anantha P., Peters, ER, Veena Kumari, Fannon, D, Raghuvanshi, Satya, Kumari, Veena, Anantha P. Anilkumar, Dominic Fannon, Raghuvanshi, S, Fannon, Dominic, Premkumar, Preethi   +28 more
core   +1 more source

What Do Content Moderators Do? Emotion Work and Control on a Digital Health Platform

Journal of Management Studies, EarlyView.
Abstract Content moderation determines the type of data displayed on platforms. Although this type of work is conducted online without interpersonal interactions, it does not remain emotionless. This article presents findings from a longitudinal qualitative study of how content moderation is conducted on a UK‐based platform that publishes patients ...
Dimitra Petrakaki, Andreas Kornelakis
wiley   +1 more source

Use of third-generation antipsychotics in combination with clozapine in the treatment of resistant schizophrenia

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The aim of the study was to analyze the pathogenesis and treatment strategies of treatment-resistant schizophrenia by searching, selecting and reviewing publications covering this topic. 42 articles were analyzed during the work, which contributed to the
A. R. Asadullin, P. O. Bomov, Yu. A. Bogod   +2 more
doaj   +1 more source

Influence of 5-HT1A and 5-HTTLPR genetic variants on the schizophrenia symptoms and occurrence of treatment-resistant schizophrenia

, 2015
Tea Terzić,1 Matej Kastelic,2 Vita Dolžan,2 Blanka Kores Plesničar11Ljubljana University Psychiatric Hospital, Ljubljana, Slovenia; 2Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana ...
Terzić T, Dolžan V, Plesničar BK, Kastelic M   +3 more
core  

Reading and relating with Frieda Fromm‐Reichmann and Joanne Greenberg

Critical Quarterly, EarlyView.
Joshua Pugh
wiley   +1 more source

Occlusal Dysesthesia: Identifying Knowledge Gaps to Advance Clinical Care

Journal of Oral Rehabilitation, EarlyView.
This scoping review highlights major knowledge gaps in the understanding of occlusal dysesthesia, including limited evidence on sensory, psychological and neurobiological mechanisms. Current theories remain largely unverified, underscoring the need for integrated biopsychosocial research to improve diagnosis and patient care.
Sara A. Esmat, Helen He, Iacopo Cioffi
wiley   +1 more source

Reintroduction of Clozapine following Neuroleptic Malignant Syndrome in a Young Patient with Resistant Schizophrenia

Case Reports in Psychiatry
The incidence of neuroleptic malignant syndrome justifies the immediate discontinuation of the drug in question and the reinstitution of therapy with another drug.
Miriam Chandad, Rajae Chlihfane, Safae Kodad, Bouchra Oneib, Fatima Elghazouani   +4 more
doaj   +1 more source