Results 181 to 190 of about 32,295 (302)

Effectiveness of a Psychiatrist‐Led Clinic for Metabolic Health in Severe Mental Illness: A Retrospective Chart Review Study

Acta Psychiatrica Scandinavica, Volume 154, Issue 1, Page 74-88, July 2026.
ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios, Femin Prasad, Riddhita De, Kateryna Maksyutynska, Akash PrasannaKumar, Vittal Korann, Tariq Ahmed, Marcos Sanches, Leah Burton, Mohammed A. Alarabi, Tanner Isinger, Michelle Desanti, Rebecca Oliveira, Daphne J. Korczak, Ariel Graff‐Guerrero, Gary Remington, Margaret K. Hahn, Sri Mahavir Agarwal   +17 more
wiley   +1 more source

In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex

British Journal of Pharmacology, Volume 183, Issue 13, Page 3723-3742, July 2026.
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome, Masaaki Ueki, Takujiro Homma, Shinji Matsunaga, Saki Shimizu, Yukihiro Ohno, Shuhei Tomita   +6 more
wiley   +1 more source

Deep brain stimulation for clozapine-resistant schizophrenia: a systematic review of target-specific outcomes and stereotactic technical considerations. [PDF]

Neurosurg Rev
Armando AR, Fahmi A, Subianto H, Turchan A, Wang W, Peng Y, Kamaruddin MF, Syaharani R, Zamzam RR, Maulina N.   +9 more
europepmc   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

Adjuvant Mood Stabilisers for Long-Term Management of Treatment-Resistant Schizophrenia: A Case Report. [PDF]

Cureus
Anyameluhor F, Elliott C.
europepmc   +1 more source

Intranasal Mucosal Atomiser Devices: A Novel Harm Reduction Intervention

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Factors associated with diminished peripheral vein access, including age, prolonged history of injecting drug use and coadministration with other substances, are all increasing among people who inject drugs in Australia. This exposes individuals to increased risk of injecting related complications, including skin and soft tissue ...
Hayden Green, Thileepan Naren, Brittany Chapman, Martyn Lloyd‐Jones, Sione Crawford, Dean Membrey   +5 more
wiley   +1 more source

Th1/Th17-linked transcription factors TBX21 and RORC were associated with clinical response to rituximab in treatment-resistant schizophrenia. [PDF]

Brain Behav Immun Health
Bylund S, Eklund D, Humble MB, Bejerot S, Wikström S.   +4 more
europepmc   +1 more source

Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1162-1172, July 2026.
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast, Bassel H. Al Wattar, Marie Beylot Barry, Holger Brüggemann, Zrinka Bukvić Mokos, Dawn M. Caruana, Klaus Degitz, Clio Dessinioti, Brigitte Dréno, Rieke J. B. Driessen, Harald Gollnick, Merete Hædersdal, Alexander Katoulis, Severin Läuchli, Julien Lambert, Alison M. Layton, Giuseppe Micali, Falk R. Ochsendorf, Thozhukat Sathyapalan, Katarina Zak Stangeland, Simon Francis Thomsen, Daniel Töröcsik, Antonia Pennitz   +22 more
wiley   +1 more source

Identifying Clinical Characteristics of Young People with Treatment-Resistant Schizophrenia Undergoing Community Initiation of Clozapine. [PDF]

Schizophr Bull
Conaty O, Thompson A, McGorry P, Gaughran F, O'Donoghue B, Lally J.   +5 more
europepmc   +1 more source

Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
GR‐A knockin mice were generated that express the classic full‐length glucocorticoid receptor (GR‐A) but lack the highly conserved translational isoforms GR‐B, GR‐C1, GR‐C2, GR‐C3, GR‐D1, GR‐D2, and GR‐D3 that have progressively shorter N‐terminal transactivation domains (NTDs).
Robert H. Oakley, Tatsuya Sueyoshi, Sivapriya Ramamoorthy, Viktoriya D. Nikolova, David R. Goulding, Jianying Li, Manas K. Ray, Sheryl S. Moy, John A. Cidlowski   +8 more
wiley   +1 more source