Results 101 to 110 of about 33,766 (287)

Local structure of REFeAsO (RE=La, Pr, Nd, Sm) oxypnictides studied by Fe K-edge EXAFS

, 2009
Local structure of REOFeAs (RE=La, Pr, Nd, Sm) system has been studied as a function of chemical pressure varied due to different rare-earth size. Fe K-edge extended X-ray absorption fine structure (EXAFS) measurements in the fluorescence mode has ...
A. BIANCONI, A. IADECOLA, B. JOSEPH, D. MAHAJAN, L. SIMONELLI, M. FILIPPI, M. FRATINI, N.L. SAINI, S. AGRESTINI   +8 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

LABELING, TRADE AND GENETICALLY MODIFIED ORGANISMS (GMOS): A PROPOSED SOLUTION [PDF]

The purpose of this brief article is to assess the current controversy over Genetically Modified Organisms (GMOs) in agriculture and its potential implications for the global trading system. More importantly, it offers a solution to the serious potential
Jackson, Lee Ann, Runge, C. Ford
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Esthetics of resistence, esthetics of revolt

Pitágoras 500, 2014
Neste artigo, pretendemos recapitular primeiramente o que se pode dizer, em linhas gerais, sobre a relação entre política, sobretudo ideologia, e teatro.
Hans-Thies Lehmann
doaj   +1 more source

A resistência dos fungos como consequência da utilização de fungicidas sistêmicos: mecanismos de resitência, monitoramento e estratégias anti-resistência. [PDF]

, 2013
A partir do surgimento dos fungicidas sistêmicos, cuja sistemicidade em termos de modernidade, revolucionou a agricultura, proporcionando-lhe opções mais avançadas para o controle eficaz de fungos causadores de doenças.
GARCIA, A.
core   +1 more source

Phonon-like and single particle dynamics in liquid lithium

, 1999
The dynamic structure factor, S(Q,E), of liquid lithium (T=475 K) has been determined by inelastic x-ray scattering (IXS) in the momentum transfer region (Q = 1.4-110 nm-1).
, A Cunsolo, Balucani U., Boon J. P., Burkel E., C Masciovecchio, De Jong P. H. K., F Sette, G Ruocco, Glyde H. R., Lovesey S. W., Oshe R. (Editors), R Verbeni, Ruocco G., Scopigno T., Silver R. N., T Scopigno, U Balucani   +17 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source