Results 71 to 80 of about 33,766 (287)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Discovery of anthelmintic resistant of nematodes of ruminants in region West Kazakhstan

open access: yesРоссийский паразитологический журнал, 2016
Annual (during 7–12 years) using fenbendasol reduces its efficiency at strongylatosis of ruminants on 29,5% at the average, but in facilities where it is used for the first time its efficiency has formed at the average on 97,4 %.
R. S. Karmaliev, B. A. Aituganov
doaj  

SENSITIVITY OF SALMONELLA ENTERITIDIS TO SELECTED ACTIVE CONSTITUENTS OF ESSENTIAL OILS IN IN VITRO CONDITIONS

open access: yesArchives of Veterinary Medicine, 2008
In spite of modern improvements in slaughter hygiene and food production techniques, prevention and therapy of infective animal diseases, especially zoonosis, is necessary because food safety has been an increasingly important public health issue.
Radomir Ratajac   +5 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

شخصية الأمير عبد القادر من منظور الآخر. ترجمة كتاب عبد القادر لقوستاف دوقا أنموذجا

open access: yesإنسانيات, 2003
Thanks to his great mastery of military strategy, his skill as statesman, his national heroism in the Algerian resistance, and also to this deep thinking on intellectual questions, and his poetic output, Emir Abdelkader was able to go beyond the borders ...
عبد القادر شرشار
doaj   +1 more source

Literature Review: Mekanisme Resistensi Kemoterapi Berbasis Platinum

open access: yesJurnal Kesehatan, 2020
Cisplatin is a type of platinum-based chemotherapy that is often used in the spectrum of solid neoplasms, including the ovaries, testicles, urinary vesicles, colorectal, lungs, and head-neck.
Amelia Rizky Khalidah
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reflextions on itinerant education on EJA: report of a specialist teacher

open access: yesRevista Educação Especial, 2010
This paper has the objective to analyse and reflect on the performance of the itinerant teacher who works with students with intellectual disabilities at Education of young and adults.
Annie Gomes Redig
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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