Results 91 to 100 of about 20,725 (257)

Leveraging the microbiome to combat antibiotic resistant gynecological infections

npj Antimicrobials and Resistance
The vaginal resistome can be considered a collection of the resistant determinants in the vaginal microbiome. Here we review the vaginal resistome including the microbes and resistant genes harbored in common gynecological infections, vaginal microbes ...
Tanya Kumar, Aryak Rekhi, Yumie Lee, Julielam Tran, Arlene Grace D. Nagtalon, Sidhant Rohatgi, Erika L. Cyphert   +6 more
doaj   +1 more source

Evaluation of changes in the faecal resistome associated with children's exposure to domestic animals and food animal production

Journal of Global Antimicrobial Resistance, 2022
: Objectives: The paediatric gut microbiota is a reservoir of antimicrobial resistance genes. Environmental factors such as a child's exposure to faecal contamination and antimicrobial resistance genes of animal origin likely shape the resistome of ...
Sara G. Cifuentes, Jay Graham, Fernanda Loayza, Carlos Saraiva, Liseth Salinas, Gabriel Trueba, Paúl A. Cárdenas   +6 more
doaj   +1 more source

Antimicrobial Resistant Factors in Klebsiella pneumoniae Strains Isolated From Urinary Tract Infections, Wound Infections, Hospital Wastewater, and Cervical Cancers From Ghana, Togo, and Benin

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is a Gram‐negative, facultatively anaerobic member of the Enterobacteriaceae that functions both as a gut commensal and a major opportunistic pathogen implicated in severe hospital and community‐acquired infections. The rapid global expansion of antimicrobial‐resistant K.
Biigba Yakubu, Santasree Banerjee
wiley   +1 more source

Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life

Frontiers in Microbiology, 2019
Polymicrobial infections of the respiratory tract due to antibiotic resistant bacteria are a great concern in patients with cystic fibrosis (CF). We therefore aimed at establishing a functional metagenomic method to analyze the nasal resistome in infants
Aurélie Allemann, Aurélie Allemann, Julia G. Kraemer, Julia G. Kraemer, Insa Korten, Insa Korten, Kathryn Ramsey, Carmen Casaulta, on Behalf of SCILD Study Group, Daniel Wüthrich, Daniel Wüthrich, Alban Ramette, Andrea Endimiani, Philipp Latzin, Markus Hilty   +14 more
doaj   +1 more source

Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]

, 2017
Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R, Guardabassi, L, Jana, B, Sigurðardóttir, H H   +3 more
core   +2 more sources

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 23: Suitability of taxonomic units notified to EFSA until September 2025

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Marianne Chemaly, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Fulvio Barizzone, Justine Dastouet, Nadya Doyle, Sandra Correia, Lieve Herman   +28 more
wiley   +1 more source

A brief multi-disciplinary review on antimicrobial resistance in medicine and its linkage to the global environmental microbiota. [PDF]

, 2013
The discovery and introduction of antimicrobial agents to clinical medicine was one of the greatest medical triumphs of the 20th century that revolutionized the treatment of bacterial infections.
Célia eManaia, Fiona eWalsh, Helmut eBürgmann, Hemda eGarelick, Henning eSørum, Leon eCantas, Leon eCantas, Lina M. Cavaco, Magdalena ePopowska, Syed Qaswar Ali Shah   +9 more
core   +3 more sources

The Versatile Mutational Resistome of Pseudomonas aeruginosa [PDF]

Frontiers in Microbiology, 2018
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for developing antimicrobial resistance to nearly all available antipseudomonal agents through the selection of chromosomal mutations, leading to the failure of the treatment of severe hospital-acquired or chronic infections.
Lopez-Causape, Carla; Cabot, Gabriel; del Barrio-Tofino, Ester; Oliver, Antonio   +4 more
openaire   +5 more sources

Population-level impacts of antibiotic usage on the human gut microbiome

Nature Communications, 2023
Here, the authors study the population-level impact of antimicrobial resistance genes (ARGs). By analyzing 8972 metagenomes and 3,096 gut microbiomes from healthy individuals not taking antibiotics, they demonstrate significant correlations between both ...
Kihyun Lee, Sebastien Raguideau, Kimmo Sirén, Francesco Asnicar, Fabio Cumbo, Falk Hildebrand, Nicola Segata, Chang-Jun Cha, Christopher Quince   +8 more
doaj   +1 more source

Seasonal resistome diversity and dissemination of WHO priority antibiotic-resistant pathogens in Lebanese estuaries [PDF]

, 2021
Wadad Hobeika, Margaux Gaschet, Marie-Cécile Ploy, Elena Buelow, Dolla Karam Sarkis, Christophe Dagot   +5 more
openalex   +1 more source