Results 61 to 70 of about 18,536 (211)

The intrinsic resistome of Klebsiella pneumoniae

International Journal of Antimicrobial Agents, 2019
Molecular epidemiology studies aiming at understanding the acquisition of antimicrobial resistance by clinical isolates of Klebsiella pneumoniae are regularly published; however, information on the genes that contribute to its characteristic phenotype of resistance to antibiotics (intrinsic resistome) is scarce. To fill this gap, a K.
Bernardini, Alejandra, Cuesta, Trinidad, Tomás, Anna, Bengoechea, José A., Martínez, José L., Sánchez, María B.   +5 more
openaire   +4 more sources

Impact of investigational microbiota therapeutic RBX2660 on the gut microbiome and resistome revealed by a placebo-controlled clinical trial

Microbiome, 2020
Background Intestinal microbiota restoration can be achieved by complementing a subject’s perturbed microbiota with that of a healthy donor. Recurrent Clostridioides difficile infection (rCDI) is one key application of such treatment.
Suryang Kwak, JooHee Choi, Tiffany Hink, Kimberly A. Reske, Kenneth Blount, Courtney Jones, Margaret H. Bost, Xiaoqing Sun, Carey-Ann D. Burnham, Erik R. Dubberke, Gautam Dantas, for the CDC Prevention Epicenter Program   +11 more
doaj   +1 more source

Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]

, 2018
The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher, Burnham, Carey-Ann D, CDC Prevention Epicenter Program,, Dantas, Gautam, Dubberke, Erik R, Hink, Tiffany, Jones, Susan, Kwon, Jennie H, Langdon, Amy, Patel, Sanket, Reske, Kimberly A, Seiler, Sondra, Sun, Xiaoqing, Wallace, Meghan   +13 more
core   +2 more sources

Moderate‐Temperature Hydrothermal Treatment Removes Detectable DNA and Antibiotic Resistance Genes From Municipal Sludge While Preserving Resource Value

Water and Environment Journal, EarlyView.
This graphical abstract shows the overall study design where dewatered wastewater sludge samples were collected and subjected to a range of HT temperatures. Measurement of nucleic acid concentration and antibiotic resistance gene profiles across temperatures showed that HT at moderate temperatures offers sustainable, scalable sludge sanitation and ARG ...
R. Sean Norman, Mirza Isanovic, Gabrielle Kartzmark, Nicole Berge   +3 more
wiley   +1 more source

Mining the Antibiotic Resistome

Chemistry & Biology, 2012
Antibiotic-producing microoganisms are a reservoir of drug resistance genes. Studies of the "antibiotic resistome" can inform antimicrobial drug discovery and explain the emergence of multidrug resistant pathogens. In this issue of Chemistry & Biology, Westman and colleagues take an alternative look at the resistome and identify genes that could be ...
openaire   +2 more sources

Unraveling the Amycolatopsis tucumanensis copper-resistome

BioMetals, 2012
Heavy metal pollution is widespread causing serious ecological problems in many parts of the world; especially in developing countries where a budget for remediation technology is not affordable. Therefore, screening for microbes with high accumulation capacities and studying their stable resistance characteristics is advisable to define cost-effective
Dávila Costa, José Sebastián, Kothe, Erika, Abate, Carlos Mauricio, Amoroso, Maria Julia del R.   +3 more
openaire   +3 more sources

Exploring the Potential Influence of the Human Gut Microbiota on the Gut Resistome: A Systematic Review

Microbiology Research
Antibiotic resistance is a global health problem. The human gut microbiome is implicated in the dynamics of antibiotic resistance acquisition and transmission, with the gut microbiota thought to play a crucial role.
Justine Fri, Mulalo Raphalalani, Lufuno Grace Mavhandu-Ramarumo, Pascal Obong Bessong   +3 more
doaj   +1 more source

A Population-Based Surveillance Study of Shared Genotypes of Escherichia coli Isolates from Retail Meat and Suspected Cases of Urinary Tract Infections. [PDF]

, 2018
There is increasing evidence that retail food may serve as a source of Escherichia coli that causes community-acquired urinary tract infections, but the impact of this source in a community is not known. We conducted a prospective, population-based study
Friedman, Cindy R, Hung-Fan, Melody, McDermott, Patrick, Riley, Lee W, Rubin, Julia, Suh, Joy, Thys, Erika, Yamaji, Reina   +7 more
core   +1 more source

One Health Genomic Analysis of Methicillin‐Resistant Staphylococcus spp. From Humans, Cats, and Dogs in a Veterinary Hospital in Central Chile

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction The emergence of methicillin‐resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. Methods We performed a comparative genomic characterisation of 49 methicillin‐resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central Chile.
Daniel Garrido, Danny Fuentes‐Castillo, Leslye Camila del Río, Jorge Barraza‐Schulmeyer, Felipe Melis, Patricia García, Carla Flores‐Yáñez, Pamela Thomson   +7 more
wiley   +1 more source

The human gut resistome

Indian Journal of Medical Research, 2019
The human gut is home to a myriad of organisms. While some are harmless commensals, others are transient, pathogenic flora. The gut microbiome is composed of diverse bacterial flora, and apart from playing a major role in protecting from various infectious and non-infectious diseases, it plays an important role in resistance ...
Singh, Shreya, Verma, Nipun, Taneja, Neelam   +2 more
openaire   +2 more sources