Results 81 to 90 of about 18,536 (211)

Vancomycin gene selection in the microbiome of urban Rattus norvegicus from hospital environment [PDF]

, 2016
Background and objectives: Widespread use of antibiotics has resulted in selection pressure on genes that make bacteria non-responsive to antibiotics. These antibiotic-resistant bacteria are currently a major threat to global health.
Andersen, Paal Skytt, Arn Hansen, Thomas, Fuursted, Kurt, Hansen, Anders Johannes, Harms, Klaus, Joshi, Tejal, Larsen, Anders Rhod, Mollerup, Sarah, Nielsen, Lars Peter, Willerslev, Eske   +9 more
core   +2 more sources

Effect of surgical antimicrobial prophylaxis duration for colic surgery on complications and resistome

Equine Veterinary Journal, Volume 58, Issue 2, Page 390-403, March 2026.
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood, Alicia Long, Jairo Perez, Scott Daniel, Kyle Bittinger, Maia Aitken, Laurel Redding   +6 more
wiley   +1 more source

The Neglected Intrinsic Resistome of Bacterial Pathogens

PLoS ONE, 2008
Bacteria with intrinsic resistance to antibiotics are a worrisome health problem. It is widely believed that intrinsic antibiotic resistance of bacterial pathogens is mainly the consequence of cellular impermeability and activity of efflux pumps. However, the analysis of transposon-tagged Pseudomonas aeruginosa mutants presented in this article shows ...
Fajardo, Alicia, Martinez-Martin, Nadia, Mercadillo, Maria, Galan, Juan, Ghysels, Bart, Matthijs, Sandra, Cornelis, Pierre, Wiehlmann, Lutz, Tümmler, Burkhard, Baquero, Fernando, Martinez, Jose Luis   +10 more
openaire   +7 more sources

Leveraging the microbiome to combat antibiotic resistant gynecological infections

npj Antimicrobials and Resistance
The vaginal resistome can be considered a collection of the resistant determinants in the vaginal microbiome. Here we review the vaginal resistome including the microbes and resistant genes harbored in common gynecological infections, vaginal microbes ...
Tanya Kumar, Aryak Rekhi, Yumie Lee, Julielam Tran, Arlene Grace D. Nagtalon, Sidhant Rohatgi, Erika L. Cyphert   +6 more
doaj   +1 more source

Temporal development and potential interactions between the gut microbiome and resistome in early childhood

Microbiology Spectrum
Antimicrobial resistance-associated infections have become a major threat to global health. The gut microbiome serves as a major reservoir of bacteria with antibiotic resistance genes; whereas, the temporal development of gut resistome during early ...
Lanlan Zhao, Xiao Yang, Yijia Liang, Ziyi Zhang, Yanwen Ding, Yihui Wang, Bin Chen, Jiacheng Wu, Chuandi Jin, Guoping Zhao, Ziyun Li, Lei Zhang   +11 more
doaj   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, Volume 3, Issue 1, March 2026.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Validated predictive modelling of the environmental resistome [PDF]

The ISME Journal, 2015
Abstract Multi-drug-resistant bacteria pose a significant threat to public health. The role of the environment in the overall rise in antibiotic-resistant infections and risk to humans is largely unknown. This study aimed to evaluate drivers of antibiotic-resistance levels across the River Thames catchment, model key biotic, spatial ...
Amos, Gregory C.A., Gozzard, Emma, Carter, Charlotte E., Mead, Andrew, Bowes, Mike J., Hawkey, Peter M., Zhang, Lihong, Singer, Andrew C., Gaze, William H., Wellington, Elizabeth M.H.   +9 more
openaire   +5 more sources

Resistome flow in global landfill systems

iMetaOmics, Volume 3, Issue 1, March 2026.
Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong, Rui Zhang, Xiaoxing Lin, Yangqing Wang, Shu Yang, Farees ud din Mufti, Yuping Yao, Guowei Zhou, Chuanwu Xi, Weixi Shu, Gordon Price, Youcai Zhao, Liyan Song   +12 more
wiley   +1 more source

Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life

Frontiers in Microbiology, 2019
Polymicrobial infections of the respiratory tract due to antibiotic resistant bacteria are a great concern in patients with cystic fibrosis (CF). We therefore aimed at establishing a functional metagenomic method to analyze the nasal resistome in infants
Aurélie Allemann, Aurélie Allemann, Julia G. Kraemer, Julia G. Kraemer, Insa Korten, Insa Korten, Kathryn Ramsey, Carmen Casaulta, on Behalf of SCILD Study Group, Daniel Wüthrich, Daniel Wüthrich, Alban Ramette, Andrea Endimiani, Philipp Latzin, Markus Hilty   +14 more
doaj   +1 more source

Mobilization of Antibiotic Resistance: Are Current Approaches for Colocalizing Resistomes and Mobilomes Useful?

Frontiers in Microbiology, 2020
Antimicrobial resistance (AMR) poses a global human and animal health threat, and predicting AMR persistence and transmission remains an intractable challenge.
Ilya B. Slizovskiy, Kingshuk Mukherjee, Christopher J. Dean, Christina Boucher, Noelle R. Noyes   +4 more
doaj   +1 more source