Results 51 to 60 of about 675,824 (339)
Phagocytosis of Apoptotic Cells in Resolution of Inflammation
Frontiers in Immunology, 2020 Efficient inflammation resolution is important not only for the termination of the inflammatory response but also for the restoration of tissue integrity. An integral process to resolution of inflammation is the phagocytosis of dying cells by macrophages,
I. Kourtzelis +2 more
semanticscholar +1 more source
Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection. [PDF]
, 2016 HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined.
Dandekar, Satya +6 more
core +1 more source
Soluble Mediators Produced by Pro-Resolving Macrophages Inhibit Angiogenesis
Frontiers in Immunology, 2018 Different subtypes of macrophages have been shown to participate in different stages of inflammation and tissue repair. In the late stage of tissue repair, the macrophages, following their engulfment of apoptotic neutrophils, acquire a new phenotype ...
Shira Michaeli +8 more
doaj +1 more source
Blame the signaling: role of cAMP for the resolution of inflammation.
Pharmacological Research, 2020 A complex intracellular signaling governs different cellular responses in inflammation. Extracellular stimuli are sensed, amplified, and transduced through a dynamic cellular network of messengers converting the first signal into a proper response ...
L. Tavares +6 more
semanticscholar +1 more source
Frontiers in Microbiology, 2018 Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas.
Rodrigo A. López-Muñoz +7 more
doaj +1 more source
The role of macrophages in the resolution of inflammation.
Journal of Clinical Investigation, 2019 Macrophages are tissue-resident or infiltrated immune cells critical for innate immunity, normal tissue development, homeostasis, and repair of damaged tissue.
Satoshi Watanabe +4 more
semanticscholar +1 more source
New Perspectives in the Study of Intestinal Inflammation: Focus on the Resolution of Inflammation
International Journal of Molecular Sciences, 2021 Inflammation is an essential physiological process that is directed to the protection of the organism against invading pathogens or tissue trauma. Most of the existing knowledge related to inflammation is focused on the factors and mechanisms that drive ...
M. Camba-Gómez +2 more
semanticscholar +1 more source
Resolvin E1 Regulates Th17 Function and T Cell Activation
Frontiers in Immunology, 2021 Resolvin E1 (RvE1) is a specialized pro-resolving lipid mediator derived from eicosapentaenoic acid and plays a critical role in resolving inflammation and tissue homeostasis. Th17 cells are a distinct group of T helper (Th) cells with tissue-destructive
Fatma Oner +10 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Cyclin-dependent kinase (CDK) inhibitor drugs (CDKi), such as R-roscovitine and AT7519, induce neutrophil apoptosis in vitro and enhance the resolution of inflammation in a number of in vivo models. This class of compounds are potential novel therapeutic
Brian J. McHugh +9 more
doaj +1 more source
ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury. [PDF]
, 2020 The complex molecular microenvironment of the wound bed regulates the duration and degree of inflammation in the wound repair process, while its dysregulation leads to impaired healing. Understanding factors controlling this response provides therapeutic
Baird, Andrew +5 more
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