Results 131 to 140 of about 44,785 (315)

Solution of the axismmetric plane thermoelasticity problem for a polar-orthotropic disc of variable thickness in the rotating thermal field by Volterra integral equation of the second kind

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2017
With the help of linear Volterra integral equation of the second kind the solution of the axisymmetric plane thermoelasticity problem for a polar-orthotropic disk of variable thickness in the rotating thermal field is generally given.
Uladzimir V. Karalevich   +1 more
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Spectral Approach to Fractional Power of Operator and Its Matrix Approximation

open access: yesFractal and Fractional
This article is devoted to constructing the fractional powers of operators and their matrix approximations. A key feature of this study is the use of a spectral approach that remains applicable even when the base operator does not generate a semigroup ...
Vassili N. Kolokoltsov   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Spectrum and resolvent of multi-channel systems with internal energies and common boundary conditions

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In the article the spectrum and resolvent of the so-called multichannel systems with nonzero internal energies were investigated. The spectrum and resolvent of multichannel Sturm-Liouville systems with non-zero internal energies mi2 and general boundary
A.A. Valiyev   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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