Results 51 to 60 of about 1,075,287 (378)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

On the extended resolvent of the Nonstationary Schrodingher operator for a Darboux transformed potential

, 2005
In the framework of the resolvent approach it is introduced a so called twisting operator that is able, at the same time, to superimpose \`a la Darboux $N$ solitons to a generic smooth decaying potential of the Nonstationary Schr\"odinger operator and to
A K Pogrebkov, Boiti M, Boiti M, Boiti M, Boiti M, Boiti M Pempinelli F Pogrebkov A K Prinari B, Dryuma V S, Dubrovin B A, F Pempinelli, Fokas A S, Fokas A S, Kadomtsev B B, M Boiti, Manakov S V, Matveev V B, Novikov S P, Pogrebkov A K, Zakharov V E   +17 more
core   +1 more source

The Resolvent of Impulsive Singular Hahn–Sturm–Liouville Operators

Annales Mathematicae Silesianae
In this study, the resolvent of the impulsive singular Hahn–Sturm– Liouville operator is considered. An integral representation for the resolvent of this operator is obtained.
Allahverdiev Bilender P., Tuna Hüseyin, Isayev Hamlet A.   +2 more
doaj   +1 more source

Analysis Of Korteweg-Type Compressible Fluid Model With Slip Boundary Conditions In 3-Dimensional Half-Space

Cauchy: Jurnal Matematika Murni dan Aplikasi
The Korteweg fluid model is typically used to describe the flow of two-phase fluids, where phase transitions occur at the interface, recognized by capillary effects.
Suma Inna, Muhammad Manaqib, Ilman Gifari   +2 more
doaj   +1 more source

Approximation of point interactions by geometric perturbations in two-dimensional domains

Bulletin of Mathematical Sciences, 2023
In this paper, we present a new type of approximation of a second-order elliptic operator in a planar domain with a point interaction. It is of a geometric nature that the approximating family consists of operators with the same symbol and regular ...
D. I. Borisov, P. Exner
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

On the relevance of Reynolds stresses in resolvent analyses of turbulent wall-bounded flows

, 2019
The ability of linear stochastic response analysis to estimate coherent motions is investigated in turbulent channel flow at friction Reynolds number Re$_\tau$ = 1007.
Cossu, Carlo, Henningson, Dan S., Morra, Pierluigi, Semeraro, Onofrio   +3 more
core   +1 more source

An invitation to resolvent analysis [PDF]

Theoretical and Computational Fluid Dynamics
Resolvent analysis is a powerful tool that can reveal the linear amplification mechanisms between the forcing inputs and the response outputs about a base flow.
L. V. Rolandi, J. Ribeiro, C. Yeh, Kunihiko Taira   +3 more
semanticscholar   +1 more source

Nonlocal problems for integrodifferential equations via resolvent operators and optimal controls

Discussiones Mathematicae Differential Inclusions Control and Optimization, 2022
In this work, we mainly consider a class of integrodifferential equations with a nonlocal initial conditions. We suppose that the linear part has a resolvent operator R ( t ) in the sense given by Grimmer. By using Hölder inequality, p-mean continuity and
M. Diop, K. Ezzinbi, M. Ly
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source