Results 31 to 40 of about 682,963 (292)

Semi rigid connections and their influence on steel column behaviour. [PDF]

open access: yes, 1980
A review of the development of the analysis of frames with semi-rigid end restraint is given, including the treatment of frame stability and effective lengths. The available experimental data relating to the moment versus in-plane
Jones, Stephen Winford
core   +6 more sources

Identification on rock and soil parameters for vibro-cutting rock by disc cutter based on fuzzy radial basis function neural network

open access: yesMATEC Web of Conferences, 2018
A single-POF model of disc cutter with rock and soil has been established according to the dynamical feature and vibration mechanism of disc cutter vibro-cutting rock to solve problem of self-adaption vibro-cutting rock for disc cutter, and ...
Chen Qiang, Lang Jianke
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Experimental Study on Damping Ratio Characteristics of Loose Silty Fine Sand at Different Saturations [PDF]

open access: yes长江科学院院报
[Objective] Current research on the damping ratio evolution of silty fine sand under varying saturation conditions remains relatively limited, and in particular, systematic investigations revealing the mechanisms by which saturation variations influence ...
YU Song, XU Meng-bing, FENG Zhi-guo, ZHANG Jun-jie, ZHANG Guo-chao, WANG Yong
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Modulus and Damping of Asphaltic Concrete Using the Resonant Column [PDF]

open access: yes, 1980
When analyzing flexible pavements or predicting their behavior by such means as elastic-layered theory or by finite elements, it is necessary to know the parameters that govern the behavior of the pavement components. One of the most important factors to
Deen, Robert C., Allen, David L.
core   +1 more source

Resonant column tests on maximum shear modulus and damping ratio of coral sand

open access: yesYantu gongcheng xuebao, 2020
The resonant column tests on the effects of relative density and confining pressure on the maximum modulus and damping ratio of coral sand in South China Sea under small strain are performed.
LI Xiao-mei 1, WANG Fang 1, HAN Lin 2, GUAN Yun-fei 1, ZHAN Xin-jie 1
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Hydrodynamic behavior of resonant chamber of an oscillating column of water for Pacific Ocean conditions

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2023
Wave energy converters (WEC) may be a promising option for extracting the energy available in the sea and oceans in a clean way. The oscillating water column (OWC) is one of the most applicable and well-known WEC systems.
Juan David Parra-Quintero   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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