Results 61 to 70 of about 75,682 (299)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Resonant column tests on maximum shear modulus and damping ratio of coral sand

open access: yesYantu gongcheng xuebao, 2020
The resonant column tests on the effects of relative density and confining pressure on the maximum modulus and damping ratio of coral sand in South China Sea under small strain are performed.
LI Xiao-mei 1, WANG Fang 1, HAN Lin 2, GUAN Yun-fei 1, ZHAN Xin-jie 1
doaj   +1 more source

Investigation of long-wavelength elastic wave propagation through wet bentonite-filled rock joints

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2023
The saturation of the compacted bentonite buffer in the deep geological repository can cause bentonite swelling, intrusion into rock fractures, and erosion.
Ji-Won Kim   +3 more
doaj   +1 more source

On the Lyman-alpha Emission of Starburst Galaxies [PDF]

open access: yes, 1993
Nearby starburst galaxies have consistently shown anomalous Ly-alpha/H-beta ratios. By re-analysing the published IUE/optical observations, we show that most starbursts present a normal Ly-alpha emission, consistent with case B recombination theory ...
Valls-Gabaud, David
core   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Strength and deformation characteristics of waste mud–solidified soil

open access: yesScientific Reports
The treatment, disposal, and resource utilization of waste mud are challenges for engineering construction. This study investigates the road performance of waste mud–solidified soil and explains how solidifying materials influence the strength and ...
Yan Tang   +6 more
doaj   +1 more source

Soil Dynamic Constitutive Model for Characterizing the Nonlinear-Hysteretic Response

open access: yesApplied Sciences, 2017
Characterization of nonlinear hysteretic responses plays a significant role in predicting soil behaviors. They are mostly described with either simple empirical functions or complex constitutive models.
Song-Hun Chong
doaj   +1 more source

Laboratory Investigation of the Mechanical Properties of a Rubber–Calcareous Sand Mixture: The Effect of Rubber Content

open access: yesApplied Sciences, 2020
This paper introduces a rubber–calcareous sand mixture as a lightweight building material in offshore engineering. The mechanical properties of mixtures of varying rubber contents were investigated by performing a one-dimensional (1-D) compression test ...
Xin Liu, Chaoyang Tian, Hengxing Lan
doaj   +1 more source

Discovery of ultra-fast outflows in a sample of Broad Line Radio Galaxies observed with Suzaku [PDF]

open access: yes, 2010
We present the results of a uniform and systematic search for blue-shifted Fe K absorption lines in the X-ray spectra of five bright Broad-Line Radio Galaxies (BLRGs) observed with Suzaku.
Ballo, L.   +7 more
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

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