Results 71 to 80 of about 902,650 (342)

The diagnostic effect of sequential detection of ADA screening and T-SPOT assay in pleural effusion patients

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Purpose To evaluate the diagnostic effect of sequential detection of Adenosine deaminase (ADA) screening and T-SPOT assay on tuberculosis (TB) pleurisy in pleural effusion patients.Materials and methods 248 pleural effusion patients (172 TB and 76 non-TB)
Mingxia Feng   +3 more
doaj   +1 more source

Direct reading of electrocardiograms and respiration rates [PDF]

open access: yes, 1969
Technique for reading heart and respiration rates is more accurate and direct than the previous method. Index of a plastic calibrated card is aligned with a point on the electrocardiogram.
Wise, J. P.
core   +1 more source

KATP Channel Openers Have Opposite Effects on Mitochondrial Respiration Under Different Energetic Conditions [PDF]

open access: yes, 2008
Mitochondrial (m) KATP channel opening has been implicated in triggering cardiac preconditioning. Its consequence on mitochondrial respiration, however, remains unclear. We investigated the effects of two different KATP channel openers and antagonists on
Camara, Amadou K.S.   +5 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

MicroRNA‐7‐5p induces cell growth inhibition, cell cycle arrest and apoptosis by targeting PAK2 in non‐small cell lung cancer

open access: yesFEBS Open Bio, 2019
MicroRNAs (miR) are known to be critical regulators in tumor progression. miR‐7‐5p was reported to be involved in several cancers, including glioblastoma, cervical cancer, and melanoma, but its prognostic value and biological function in non‐small‐cell ...
Qin Li   +4 more
doaj   +1 more source

Antibiotics for treatment of acute exacerbation of chronic obstructive pulmonary disease: a network meta-analysis

open access: yesBMC Pulmonary Medicine, 2017
Background Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate.
Hai-Lin Zhang   +4 more
doaj   +1 more source

Apnea Monitor Based on Bluetooth with Android Interface [PDF]

open access: yes, 2019
Apnea monitor is a device that is used to give a warning if there is stop breathing. Stop breathing while sleeping is one form of obstructive sleep apnea.
Made Wirayuda, I Dewa   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Nomogram for Predicting Efficacy and Prognosis After Chemotherapy for Advanced NSCLC

open access: yesThe Clinical Respiratory Journal
Purpose One major issue is the therapeutic effect following chemotherapy for non–small cell lung cancer (NSCLC). Although numerous risk factors have been identified and novel therapies have been developed, improving patient overall survival (OS) remains ...
Jiaying Gao   +6 more
doaj   +1 more source

Preliminary analysis of gut microbiome characteristics in children with obstructive sleep apnea hypopnea syndrome

open access: yesFrontiers in Neurology
ObjectiveTo analyze the characteristic changes in the gut microbiome in children with obstructive sleep apnea-hypopnea syndrome (OSAHS) and to investigate the relationship between the gut microbiome and polysomnography (PSG) results.MethodsChildren ...
Zhihui Wang   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy