Results 71 to 80 of about 1,062,445 (387)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Widespread inhibition of daytime ecosystem respiration

open access: yesNature Ecology & Evolution, 2019
The global land surface absorbs about a third of anthropogenic emissions each year, due to the difference between two key processes: ecosystem photosynthesis and respiration.
T. Keenan   +6 more
semanticscholar   +1 more source

Extra-matrix Mg\u3csup\u3e2+\u3c/sup\u3e Limits Ca\u3csup\u3e2+\u3c/sup\u3e Uptake and Modulates Ca\u3csup\u3e2+\u3c/sup\u3e Uptake-independent Respiration and Redox State in Cardiac Isolated Mitochondria [PDF]

open access: yes, 2013
Cardiac mitochondrial matrix (m) free Ca2+ ([Ca2+]m) increases primarily by Ca2+ uptake through the Ca2+ uniporter (CU). Ca2+ uptake via the CU is attenuated by extra-matrix (e) Mg2+ ([Mg2+]e).
Blomeyer, Christoph A.   +5 more
core   +1 more source

On Physical and Mental Fatigue [PDF]

open access: yes, 1966
In this experiment the comparison was studied between the muscular and the nervous fatigue and the flicker phenomenal value of the optic nerve. In order to measure the physical fatigue, various methods have been reported by many authers.
Harano, Hiromi   +2 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Association of PM2.5 and PM10 with Acute Exacerbation of Chronic Obstructive Pulmonary Disease at lag0 to lag7: A Systematic Review and Meta-Analysis

open access: yesCOPD, 2022
This study aimed to conduct a meta-analysis to investigate whether short-term exposure to fine (PM2.5) and coarse (PM10) particulate matter was associated with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) hospitalization ...
Niuniu Li   +3 more
doaj   +1 more source

A Randomized Controlled Trial of Device Guided, Slow-Paced Respiration in Women with Overactive Bladder Syndrome. [PDF]

open access: yes, 2019
PurposeWe evaluated the effects of device guided, slow-paced respiration on urgency associated urinary symptoms, perceived stress and anxiety, and autonomic function in women with overactive bladder syndrome.Materials and methodsWe performed a randomized,
Grady, Deborah   +5 more
core   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Interleukin-4 and interferon gamma in bronchial remodeling in asthma patients with cold airway hyperresponsiveness

open access: yesБюллетень сибирской медицины
Interleukin-4 (IL-4) and interferon gamma (IFNγ) are key participants in the polarization of the immune response toward Th1 or Th2 types in bronchial asthma.
A. B. Pirogov   +5 more
doaj   +1 more source

MIR205HG acts as a ceRNA to expedite cell proliferation and progression in lung squamous cell carcinoma via targeting miR-299-3p/MAP3K2 axis

open access: yesBMC Pulmonary Medicine, 2020
Introduction Long noncoding RNAs (lncRNAs) have been associated with many types of cancers, but their molecular mechanisms in lung squamous cell carcinoma (LUSC) have not been fully studied.
Limin Liu   +5 more
doaj   +1 more source

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