Results 1 to 10 of about 228,839 (261)

Respiratory Depression Following Concomitant Infusion of Remimazolam and Remifentanil Using Targeted Effect-Site Concentrations: A Randomized Controlled Trial [PDF]

Medicina
Background and Objectives: Remimazolam and remifentanil are ultra-short-acting agents that are used for sedation and analgesia, respectively. Their combined effect on respiratory function is unclear.
Ha Yeon Kim, Sang Kee Min, Jee Hwan Moon, Hyeongjin Kwak, Soo Jung Park   +4 more
doaj   +2 more sources

Prognostic Value of Long Corrected QT Interval on Electrocardiogram in Acute Organophosphate Poisoning: A Cohort Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: According to data available from National Poison Information Centre India, suicidal poisoning with household agents (organophosphates, carbamates etc.,) is the most common modality of poisoning.
Jayshree Gamit, Archana Gandhi
doaj   +1 more source

Opioid suppression of an excitatory pontomedullary respiratory circuit by convergent mechanisms

eLife, 2023
Opioids depress breathing by inhibition of interconnected respiratory nuclei in the pons and medulla. Mu opioid receptor (MOR) agonists directly hyperpolarize a population of neurons in the dorsolateral pons, particularly the Kölliker-Fuse (KF) nucleus ...
Jordan T Bateman, Erica S Levitt
doaj   +1 more source

Clonidine Poisoning in A Child-A case report [PDF]

Asia Pacific Journal of Medical Toxicology, 2021
Introduction: Clonidine is among the drugs that are in a list of ‘one pill can kill’ drugs. We are reporting a child with clonidine toxicity with classical manifestations who recovered completely.
Jagadishkumar K, Sneha Ramesh, MOHAMMED ROSHAN, KRISHNAKUMAR H C   +3 more
doaj   +1 more source

Opioid-induced respiratory depression increases hospital costs and length of stay in patients recovering on the general care floor

BMC Anesthesiology, 2021
Background Opioid-induced respiratory depression is common on the general care floor. However, the clinical and economic burden of respiratory depression is not well-described. The PRediction of Opioid-induced respiratory Depression In patients monitored
Ashish K. Khanna, Leif Saager, Sergio D. Bergese, Carla R. Jungquist, Hiroshi Morimatsu, Shoichi Uezono, Lian Kah Ti, Roy Soto, Wei Jiang, Wolfgang Buhre   +9 more
doaj   +1 more source

Capnography monitoring in the Post Anaesthesia Care Unit (PACU)

Journal of Perioperative Nursing, 2021
Problem identification: Capnography monitoring has been identified as a valuable monitoring tool to assist in the early detection of respiratory adverse events in postoperative patients in the PACU who are receiving supplemental oxygen.
Casandra Wilks, Paula Foran
doaj   +1 more source

Opioid-Induced In-Hospital Deaths: A 10-Year Review of Australian Coroners’ Cases Exploring Similarities and Lessons Learnt

Pharmacy, 2021
Although opioids are the cornerstone of moderate-to-severe acute pain management they are appropriately recognised as high-risk medicines. Patient and health service delivery factors can contribute to an increased risk of death associated with excessive ...
Nicholas Smoker, Ben Kirsopp, Jacinta Lee Johnson   +2 more
doaj   +1 more source

Toxicokinetic/Toxicodynamic Interaction Studies in Rats between the Drugs of Abuse γ-Hydroxybutyric Acid and Ketamine and Treatment Strategies for Overdose

Pharmaceutics, 2021
γ-hydroxybutyric acid (GHB) is widely abused alone and in combination with other club drugs such as ketamine. GHB exhibits nonlinear toxicokinetics, characterized by saturable metabolism, saturable absorption and saturable renal reabsorption mediated by ...
Nisha V. Kwatra, Marilyn E. Morris
doaj   +1 more source

Analgesic efficacy and risk of low-to-medium dose intrathecal morphine in patients undergoing cardiac surgery: An updated meta-analysis

Frontiers in Medicine, 2022
BackgroundTo evaluate the analgesic efficacy and risk of low-to-medium dose intrathecal morphine (ITM) (i.e., ≤0.5 mg) following cardiac surgery.MethodsMedline, Cochrane Library, Google scholar and EMBASE databases were searched from inception to ...
I-Wen Chen, Cheuk-Kwan Sun, Cheuk-Kwan Sun, Ching-Chung Ko, Ching-Chung Ko, Ching-Chung Ko, Pei-Han Fu, I-Chia Teng, Wei-Cheng Liu, Chien-Ming Lin, Kuo-Chuan Hung   +10 more
doaj   +1 more source

Fentanyl Patches Usage in Children; Inappropriate Use May Be Death

Journal of Pediatric Emergency and Intensive Care Medicine, 2020
The use of transdermal fentanyl has increased in recent years, especially in patients with chronic pain. However, inappropriate use may have serious consequences.
Ayşegül Alpcan, Serkan Tursun, Ozan Ürem, Ümit Ayşe Tandırcıoğlu, Gülçin Aydın, Didem Aliefendioğlu   +5 more
doaj   +1 more source