Results 171 to 180 of about 228,839 (261)

Isfahan Artificial Intelligence Event 2024, Challenge I: Respiratory Depression Detection. [PDF]

J Med Signals Sens
Kenari AR, Esmaeili N, Tajmirriahi M, Khashei M, Ebrahimpour M, Alinezhad P, Sheikhi E, Loghmani A, Torabi MR, Abruee M, Kiani M, Nekouei F, Fakhar MY, Saghaei M, Moradi MH, Rabbani H.   +15 more
europepmc   +1 more source

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

iNew Medicine, EarlyView.
ABSTRACT Objective Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer’s disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD ...
Xuerui Pang, Linbo Xie, Mengdan Chen, Yi Ji, Yibing Yan, Shanshan Zhou, Panpan Hu, Xingqi Wu, Kai Wang   +8 more
wiley   +1 more source

Predicting the Risk of Opioid-induced Respiratory Depression Using ChatGPT-4o and Machine Learning Techniques. [PDF]

Arch Acad Emerg Med
Meshkini M, Hosseini SM, Erfan Talab Evini P, Rahimi M, Mostafazadeh B, Eini P, Babaeian Amini N, Faghihi A, Esmailsorkh F, Karimi S, Asadi M, Jalilvand H, Rady Raz N, Alidadyani I, Jafari H, Zandiyeh F, Khorshidi K, Ahadi M, Ashrafi-Esfahani S, Shadnia S.   +19 more
europepmc   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Respiratory Depression in Non-Operating Room Anesthesia: An Overview. [PDF]

J Clin Med
Royz IE, Clevenger NB, Bochenek A, Locke AR, Greenberg SB.   +4 more
europepmc   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Capnography-detected respiratory depression during procedural sedation with remimazolam versus propofol: a randomised trial. [PDF]

Sci Rep
Kim J, Lee S, Jeong JS, Ahn HJ, Lee SH, Jo S, Kim W, Lee SY.   +7 more
europepmc   +1 more source

Cytotoxic and Oxidative Effects of Common Pesticides on Hepatic and Renal Cell Lines (HepG2 and Hek‐293): Implications for Human Health and Environmental Safety

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modern agricultural practices expose humans and the environment to numerous chemical pesticides. Increasing evidence suggests that commercial pesticide formulations may exhibit toxicological properties that differ from those of their active ingredients alone due to the presence of co‐formulants and additives. This study evaluated the cytotoxic
Fares Elghali, Kawther Bedchich, Nour Kacem, Mohamed Sami Aifa   +3 more
wiley   +1 more source

Intranasal Naloxone Reversal of Opioid-induced Respiratory Depression in Opioid-naive Individuals and Self-reported Daily Opioid Users. [PDF]

Anesthesiology
van Lemmen MA, Florian J, Li Z, van Velzen M, Olofsen E, Dahan A, Niesters M, Sarton E, van der Schrier R.   +8 more
europepmc   +1 more source

A Novel Application of the Volumetric Absorptive Micro Sampling Strategy to Quantify Dexmedetomidine in Capillary Blood Using an LC–MS/MS Method

Journal of Clinical Laboratory Analysis, EarlyView.
This study introduces a novel application of MITRA devices for collecting capillary blood to quantify dexmedetomidine using a newly developed and validated LC–MS/MS method. The highly sensitive developed method was successfully applied to analyze patient whole blood samples.
Lorena Lucatello, Martina Franzin, Gabriele Stocco, Jenny Bua, Francesca Cossovel, Riccardo Addobbati, Francesca Capolongo   +6 more
wiley   +1 more source