Results 71 to 80 of about 12,303,189 (383)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Mortality among Lifelong Nonsmokers Exposed to Secondhand Smoke at Home: Cohort Data and Sensitivity Analyses [PDF]

, 2006
Evidence is growing that secondhand smoke can cause death from several diseases. The association between household exposure to secondhand smoke and disease-specific mortality was examined in two New Zealand cohorts of lifelong nonsmokers (‘‘never smokers’
Blakely, Tony, Hill, Sarah, Kawachi, Ichiro, Woodward, Alistair   +3 more
core   +2 more sources

Diagnosis and management of NSAID‐Exacerbated Respiratory Disease (N‐ERD)—a EAACI position paper

Allergy. European Journal of Allergy and Clinical Immunology, 2018
NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma and/or chronic rhinosinusitis with nasal polyps (CRSwNP), symptoms of which are exacerbated by ...
M. Kowalski, I. Agache, S. Bavbek, A. Bakırtaş, M. Blanca, G. Bochenek, M. Bonini, E. Heffler, L. Klimek, T. Laidlaw, J. Mullol, E. Nizankowska-Mogilnicka, Hae‐Sim Park, M. Sanak, M. Sánchez-Borges, S. Sánchez-García, G. Scadding, M. Taniguchi, M. Torres, Andrew A. White, A. Wardzyńska   +20 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Efficacy and safety of intrapleural administration of sodium bicarbonate in patients with acute empyema and complicated parapneumonic effusion: protocol for a prospective, single-arm, interventional study

BMC Infectious Diseases
Background The standard treatment for acute empyema/complicated parapneumonic effusion (CPPE) is antibiotic administration and continuous chest drainage.
Yuichiro Suzukawa, Shuhei Teranishi, Sachi Takakura, Ryo Nakadegawa, Shunsuke Okazaki, Anna Tanaka, Shinya Matsushita, Tatsuya Muraoka, Tomofumi Hirose, Chihiro Maeda, Kenichi Seki, Ken Tashiro, Nobuaki Kobayashi, Masaki Yamamoto, Makoto Kudo, Takeshi Kaneko   +15 more
doaj   +1 more source

High-dose N-acetylcysteine for long-term, regular treatment of early-stage chronic obstructive pulmonary disease (GOLD I–II): study protocol for a multicenter, double-blinded, parallel-group, randomized controlled trial in China

Trials, 2020
Introduction The presence of increased oxidative stress and airway inflammation has been proven in subjects with chronic obstructive pulmonary disease (COPD).
Heshen Tian, Yumin Zhou, Longhui Tang, Fan Wu, Zhishan Deng, Bijia Lin, Peiyu Huang, Shaodan Wei, Dongxing Zhao, Jingping Zheng, Nanshan Zhong, Pixin Ran   +11 more
doaj   +1 more source

High-throughput next-generation sequencing for identifying pathogens during early-stage post-lung transplantation

BMC Pulmonary Medicine, 2021
Background High-throughput next-generation sequencing (HT-NGS) has the potential to detect a large variety of pathogens; however, the application of HT-NGS in lung transplant (LTx) recipients remains limited.
Qiao-yan Lian, Ao Chen, Jian-heng Zhang, Wei-jie Guan, Xin Xu, Bing Wei, Dan-xia Huang, Jian-xing He, Chun-rong Ju   +8 more
doaj   +1 more source

Exposure to the Dental Environment and Prevalence of Respiratory Illness in Dental Student Populations [PDF]

, 2004
Objective: To determine if the prevalence of respiratory disease among dental students and dental residents varies with their exposure to the clinical dental environment.
Chen, Casey, Dentino, Andrew R., DiTolla, Maris, Ho, Alex W., Scannapieco, Frank A.   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A rigorous statistical framework for spatio-temporal pollution prediction and estimation of its long-term impact on health [PDF]

, 2016
In the United Kingdom, air pollution is linked to around 40000 premature deaths each year, but estimating its health effects is challenging in a spatio-temporal study.
Lee, Duncan, Mukhopadhyay, Sabyasachi, Rushworth, Alastair, Sahu, Sujit K.   +3 more
core   +1 more source