Results 81 to 90 of about 10,890,615 (391)

Inhaled Therapy in Respiratory Disease: The Complex Interplay of Pulmonary Kinetic Processes

Canadian Respiratory Journal, 2018
The inhalation route is frequently used to administer drugs for the management of respiratory diseases such as asthma or chronic obstructive pulmonary disease.
J. M. Borghardt, C. Kloft, Ashish Sharma
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Differences of clinical features and prognosis between Mycoplasma pneumoniae necrotizing pneumonia and non-Mycoplasma pneumoniae necrotizing pneumonia in children

BMC Infectious Diseases, 2021
Background In the past few years, Mycoplasma pneumoniae (Shi et al. Lancet 390:946–958, 2017) infection has been reported more in China. However, there are few studies on the clinical characteristics and prognosis of necrotizing pneumonia (NP) (Griffiths
Beilei Yang, Weili Zhang, Wenjing Gu, Xinxing Zhang, Meijuan Wang, Li Huang, Canhong Zhu, Yongdong Yan, Wei Ji, Huiping Ni, Zhengrong Chen   +10 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Respiratory Diseases

, 2012
▪. Pulmonary arteriovenous fistulas have congenital and hereditary etiology, and patients are at risk for life-threatening rupture requiring surgery. ▪. Wegener's granulomatosis can affect any organ system, although renal and pulmonary involvement is most common; men ages 40 to 50 are at increased risk. ▪.
Heather W. Barron, Karen L. Rosenthal
openaire   +4 more sources

Visibility, wind speed, and dew point temperature are important factors in SARS‐CoV‐2 transmissibility

Pulmonary Circulation, 2022
The aim of this study is to provide evidence for the influencing factors of severe acute respiratory syndrome coronavirus 2 (SARS‐COV‐2) virus mutation by determining the impact of geographical and meteorological factors on SARS‐CoV‐2 transmission, and ...
Dansha Zhou, Elizabeth W. Wang, Chi Hou, Jing Liao, Jiarui Zhang, Xin Fu, Jiyuan Chen, Yue Xing, Wei Hong, Zhe Zhang, Yuanwei Chen, Huazhuo Feng, Yilin Chen, Qifeng Yang, Huosheng Zhang, Zicong Li, Weici Feng, Ting Wang, Ziying Lin, Chenting Zhang, Kai Yang, Wenju Lu, Jian Wang, Yuqin Chen   +23 more
doaj   +1 more source

Deep auscultation: Predicting respiratory anomalies and diseases via recurrent neural networks [PDF]

arXiv, 2019
Respiratory diseases are among the most common causes of severe illness and death worldwide. Prevention and early diagnosis are essential to limit or even reverse the trend that characterizes the diffusion of such diseases. In this regard, the development of advanced computational tools for the analysis of respiratory auscultation sounds can become a ...
arxiv  

Sleep in chronic respiratory disease: COPD and hypoventilation disorders

European Respiratory Review, 2019
COPD and obstructive sleep apnoea (OSA) are highly prevalent and different clinical COPD phenotypes that influence the likelihood of comorbid OSA.
W. McNicholas, Daniel Hansson, S. Schiza, L. Grote   +3 more
semanticscholar   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

End-to-End AI-Based Point-of-Care Diagnosis System for Classifying Respiratory Illnesses and Early Detection of COVID-19 [PDF]

arXiv, 2020
Respiratory symptoms can be a caused by different underlying conditions, and are often caused by viral infections, such as Influenza-like illnesses or other emerging viruses like the Coronavirus. These respiratory viruses, often, have common symptoms, including coughing, high temperature, congested nose, and difficulty breathing.
arxiv